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Thal_1448 Thal_1448 mutS mutS Thal_0955 Thal_0955 Thal_1223 Thal_1223 Thal_1449 Thal_1449 lgt lgt Thal_1447 Thal_1447 Thal_1453 Thal_1453 hisD hisD Thal_1451 Thal_1451 groL groL
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
Thal_1448KEGG: psa:PST_3670 DNA mismatch repair protein; TIGRFAM: DNA mismatch repair protein MutL; PFAM: DNA mismatch repair protein domain protein; ATP-binding region ATPase domain protein; Belongs to the DNA mismatch repair MutL/HexB family. (426 aa)    
Predicted Functional Partners:
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
 0.999
Thal_0955
KEGG: tgr:Tgr7_0087 DNA polymerase I; PFAM: 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2.
   
 0.983
Thal_1223
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.967
Thal_1449
PFAM: tRNA synthetase class II (G H P and S); KEGG: gme:Gmet_3259 ATP phosphoribosyltransferase regulatory subunit.
       0.806
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
 
     0.799
Thal_1447
TIGRFAM: thioredoxin reductase; KEGG: pca:Pcar_0114 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A.
     
 0.790
Thal_1453
KEGG: pca:Pcar_1881 signal peptide peptidase SppA, 67K type; TIGRFAM: signal peptide peptidase SppA, 36K type; PFAM: peptidase S49.
     
 0.769
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
       0.768
Thal_1451
Hypothetical protein.
       0.768
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
 
   
 0.678
Your Current Organism:
Thermocrinis albus
NCBI taxonomy Id: 638303
Other names: T. albus DSM 14484, Thermocrinis albus DSM 14484, Thermocrinis albus HI 11/12, Thermocrinis albus str. DSM 14484, Thermocrinis albus strain DSM 14484
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