node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFY21927.1 | dnaE1 | PputUW4_04737 | PputUW4_01103 | Exonuclease; [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. | [L] COG0587 DNA polymerase III, alpha subunit. | 0.963 |
AFY21927.1 | dnaN | PputUW4_04737 | PputUW4_00002 | Exonuclease; [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.971 |
AFY21927.1 | dnaQ | PputUW4_04737 | PputUW4_02878 | Exonuclease; [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. | DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.919 |
AFY21927.1 | dnaX | PputUW4_04737 | PputUW4_03578 | Exonuclease; [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. | DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.973 |
AFY21927.1 | holA | PputUW4_04737 | PputUW4_04772 | Exonuclease; [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. | [L] COG1466 DNA polymerase III, delta subunit. | 0.956 |
AFY21927.1 | holB | PputUW4_04737 | PputUW4_04027 | Exonuclease; [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. | DNA polymerase III subunit delta; [L] COG0470 ATPase involved in DNA replication. | 0.922 |
AFY21927.1 | polA | PputUW4_04737 | PputUW4_00070 | Exonuclease; [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.585 |
dnaA | dnaE1 | PputUW4_00001 | PputUW4_01103 | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | [L] COG0587 DNA polymerase III, alpha subunit. | 0.653 |
dnaA | dnaN | PputUW4_00001 | PputUW4_00002 | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.984 |
dnaA | dnaX | PputUW4_00001 | PputUW4_03578 | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.497 |
dnaA | polA | PputUW4_00001 | PputUW4_00070 | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.561 |
dnaE1 | AFY21927.1 | PputUW4_01103 | PputUW4_04737 | [L] COG0587 DNA polymerase III, alpha subunit. | Exonuclease; [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. | 0.963 |
dnaE1 | dnaA | PputUW4_01103 | PputUW4_00001 | [L] COG0587 DNA polymerase III, alpha subunit. | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.653 |
dnaE1 | dnaN | PputUW4_01103 | PputUW4_00002 | [L] COG0587 DNA polymerase III, alpha subunit. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.978 |
dnaE1 | dnaQ | PputUW4_01103 | PputUW4_02878 | [L] COG0587 DNA polymerase III, alpha subunit. | DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.969 |
dnaE1 | dnaX | PputUW4_01103 | PputUW4_03578 | [L] COG0587 DNA polymerase III, alpha subunit. | DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.978 |
dnaE1 | holA | PputUW4_01103 | PputUW4_04772 | [L] COG0587 DNA polymerase III, alpha subunit. | [L] COG1466 DNA polymerase III, delta subunit. | 0.972 |
dnaE1 | holB | PputUW4_01103 | PputUW4_04027 | [L] COG0587 DNA polymerase III, alpha subunit. | DNA polymerase III subunit delta; [L] COG0470 ATPase involved in DNA replication. | 0.972 |
dnaE1 | polA | PputUW4_01103 | PputUW4_00070 | [L] COG0587 DNA polymerase III, alpha subunit. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.651 |
dnaN | AFY21927.1 | PputUW4_00002 | PputUW4_04737 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exonuclease; [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. | 0.971 |