node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFY17384.1 | cysN | PputUW4_00176 | PputUW4_00796 | NLPA lipofamily protein; [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen. | Sulfate adenylyltransferase subunit 1; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.560 |
AFY17384.1 | metF | PputUW4_00176 | PputUW4_05079 | NLPA lipofamily protein; [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen. | [E] COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.409 |
AFY17384.1 | metH | PputUW4_00176 | PputUW4_02354 | NLPA lipofamily protein; [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen. | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.425 |
AFY17384.1 | metI1 | PputUW4_00176 | PputUW4_00060 | NLPA lipofamily protein; [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen. | [P] COG2011 ABC-type metal ion transport system, permease component. | 0.993 |
AFY17384.1 | metI2 | PputUW4_00176 | PputUW4_00183 | NLPA lipofamily protein; [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen. | [P] COG2011 ABC-type metal ion transport system, permease component. | 0.993 |
AFY17384.1 | metK | PputUW4_00176 | PputUW4_05068 | NLPA lipofamily protein; [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.416 |
AFY17384.1 | metN | PputUW4_00176 | PputUW4_00061 | NLPA lipofamily protein; [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen. | DL-methionine transporter ATP-binding subunit; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.989 |
AFY17384.1 | metN-2 | PputUW4_00176 | PputUW4_00184 | NLPA lipofamily protein; [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen. | ABC transporter family protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.989 |
AFY17384.1 | metQ1 | PputUW4_00176 | PputUW4_00059 | NLPA lipofamily protein; [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen. | D-methionine-binding lipoprotein; [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen. | 0.901 |
AFY17384.1 | metQ2 | PputUW4_00176 | PputUW4_00185 | NLPA lipofamily protein; [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen. | D-methionine-binding lipoprotein; [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen. | 0.923 |
cysN | AFY17384.1 | PputUW4_00796 | PputUW4_00176 | Sulfate adenylyltransferase subunit 1; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | NLPA lipofamily protein; [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen. | 0.560 |
cysN | metF | PputUW4_00796 | PputUW4_05079 | Sulfate adenylyltransferase subunit 1; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | [E] COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.518 |
cysN | metH | PputUW4_00796 | PputUW4_02354 | Sulfate adenylyltransferase subunit 1; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.566 |
cysN | metK | PputUW4_00796 | PputUW4_05068 | Sulfate adenylyltransferase subunit 1; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.474 |
cysN | metQ1 | PputUW4_00796 | PputUW4_00059 | Sulfate adenylyltransferase subunit 1; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | D-methionine-binding lipoprotein; [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen. | 0.560 |
cysN | metQ2 | PputUW4_00796 | PputUW4_00185 | Sulfate adenylyltransferase subunit 1; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | D-methionine-binding lipoprotein; [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen. | 0.560 |
metF | AFY17384.1 | PputUW4_05079 | PputUW4_00176 | [E] COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | NLPA lipofamily protein; [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen. | 0.409 |
metF | cysN | PputUW4_05079 | PputUW4_00796 | [E] COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Sulfate adenylyltransferase subunit 1; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.518 |
metF | metH | PputUW4_05079 | PputUW4_02354 | [E] COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.997 |
metF | metK | PputUW4_05079 | PputUW4_05068 | [E] COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.772 |