node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
era | rlmB | PputUW4_00959 | PputUW4_00462 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 23S rRNA (guanosine-2'-O-)-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 0.647 |
era | rlmH | PputUW4_00959 | PputUW4_04784 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | rRNA large subunit methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.502 |
era | rplO | PputUW4_00959 | PputUW4_04865 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.421 |
era | rsfS | PputUW4_00959 | PputUW4_04785 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.406 |
era | trmE | PputUW4_00959 | PputUW4_05439 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.729 |
era | ysxC | PputUW4_00959 | PputUW4_00071 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.762 |
rlmB | era | PputUW4_00462 | PputUW4_00959 | 23S rRNA (guanosine-2'-O-)-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.647 |
rlmB | rplC | PputUW4_00462 | PputUW4_04884 | 23S rRNA (guanosine-2'-O-)-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.808 |
rlmB | rplN | PputUW4_00462 | PputUW4_04874 | 23S rRNA (guanosine-2'-O-)-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.672 |
rlmB | rplO | PputUW4_00462 | PputUW4_04865 | 23S rRNA (guanosine-2'-O-)-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.829 |
rlmB | rplQ | PputUW4_00462 | PputUW4_04858 | 23S rRNA (guanosine-2'-O-)-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | [J] COG0203 Ribosomal protein L17. | 0.785 |
rlmB | rplU | PputUW4_00462 | PputUW4_04676 | 23S rRNA (guanosine-2'-O-)-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.783 |
rlmB | rsfS | PputUW4_00462 | PputUW4_04785 | 23S rRNA (guanosine-2'-O-)-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.835 |
rlmB | trmE | PputUW4_00462 | PputUW4_05439 | 23S rRNA (guanosine-2'-O-)-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.814 |
rlmB | ysxC | PputUW4_00462 | PputUW4_00071 | 23S rRNA (guanosine-2'-O-)-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.817 |
rlmH | era | PputUW4_04784 | PputUW4_00959 | rRNA large subunit methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.502 |
rlmH | rplU | PputUW4_04784 | PputUW4_04676 | rRNA large subunit methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.426 |
rlmH | rsfS | PputUW4_04784 | PputUW4_04785 | rRNA large subunit methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.952 |
rlmH | trmE | PputUW4_04784 | PputUW4_05439 | rRNA large subunit methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.476 |
rlmH | ysxC | PputUW4_04784 | PputUW4_00071 | rRNA large subunit methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.699 |