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aceE1 aceE1 aceF1 aceF1 aceF2 aceF2 lpdA1 lpdA1 lpdA2 lpdA2 lpdA3 lpdA3 pycB pycB pyk1 pyk1 pyk2 pyk2 maeB maeB ppsA ppsA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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aceE1Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (881 aa)    
Predicted Functional Partners:
aceF1
Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.997
aceF2
Dihydrolipoamide acetyltransferase; [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.
 
 0.987
lpdA1
[C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
  
 
 0.939
lpdA2
[C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
  
 
 0.939
lpdA3
[C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
  
 
 0.939
pycB
[C] COG5016 Pyruvate/oxaloacetate carboxyltransferase.
  
 
 0.921
pyk1
[G] COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.919
pyk2
[G] COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.919
maeB
[C] COG0281 Malic enzyme.
    
 0.918
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
     
 0.916
Your Current Organism:
Pseudomonas sp. UW4
NCBI taxonomy Id: 1207075
Other names: P. sp. UW4
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