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smtA smtA AFY17774.1 AFY17774.1 AFY17776.1 AFY17776.1 cmoA cmoA AFY17777.1 AFY17777.1 AFY20065.1 AFY20065.1 AFY17773.1 AFY17773.1 pvdD pvdD cmoB cmoB mnmC mnmC AFY18506.1 AFY18506.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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smtAS-adenosylmethionine-dependent methyltransferase; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family. (249 aa)    
Predicted Functional Partners:
AFY17774.1
Hypothetical protein; [R] COG1694 Predicted pyrophosphatase.
       0.807
AFY17776.1
Lipoprotein.
       0.765
cmoA
Methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
 
 
 0.657
AFY17777.1
Putative lipoprotein.
       0.638
AFY20065.1
Metallophosphoesterase; [T] COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases.
 
 
   0.635
AFY17773.1
Hypothetical protein.
 
     0.593
pvdD
[Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.582
cmoB
Methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
 
   
 0.579
mnmC
5-methylaminomethyl-2-thiouridine methyltransferase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.
  
 
 
 0.511
AFY18506.1
[S] COG3100 Uncharacterized protein conserved in bacteria.
 
     0.499
Your Current Organism:
Pseudomonas sp. UW4
NCBI taxonomy Id: 1207075
Other names: P. sp. UW4
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