STRINGSTRING
lptA lptA lptC lptC AFY17985.1 AFY17985.1 lptD lptD kdsC kdsC kdsD kdsD AFY17993.1 AFY17993.1 omlA omlA AFY17994.1 AFY17994.1 yaeT yaeT rpoN rpoN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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lptAOstA family protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. (182 aa)    
Predicted Functional Partners:
lptC
Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
 
 
 0.989
AFY17985.1
ABC transporter family protein; [R] COG1137 ABC-type (unclassified) transport system, ATPase component.
  
  
 0.965
lptD
Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
 
 
 0.858
kdsC
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.
  
  
 0.848
kdsD
Arabinose 5-phosphate isomerase; [M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation.
  
  
 0.840
AFY17993.1
Toluene tolerance protein; [Q] COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component.
 
  
 0.817
omlA
Outer membrane lipoprotein OmlA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
  
 0.687
AFY17994.1
Anti-sigma-factor antagonist (STAS); [T] COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).
 
     0.627
yaeT
Outer membrane protein assembly complex,YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
  
 0.598
rpoN
RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.596
Your Current Organism:
Pseudomonas sp. UW4
NCBI taxonomy Id: 1207075
Other names: P. sp. UW4
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