STRINGSTRING
hisC1 hisC1 hisB hisB hisD hisD aroA aroA pheA pheA AFY21913.1 AFY21913.1 hisG hisG dadA1 dadA1 AFY20529.1 AFY20529.1 AFY20662.1 AFY20662.1 AFY21107.1 AFY21107.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
hisC1[E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (350 aa)    
Predicted Functional Partners:
hisB
[E] COG0131 Imidazoleglycerol-phosphate dehydratase.
 
 0.994
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 0.994
aroA
Bifunctional cyclohexadienyldehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
 
 0.987
pheA
Chorismate mutase/prephenate dehydrogenase; [E] COG0077 Prephenate dehydratase.
  
 
 0.954
AFY21913.1
[ER] COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins.
    
 0.920
hisG
ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
 
  
 0.918
dadA1
D-amino acid dehydrogenase small subunit; Oxidative deamination of D-amino acids.
  
 
 0.915
AFY20529.1
[E] COG0436 Aspartate/tyrosine/aromatic aminotransferase.
 
 
0.913
AFY20662.1
[E] COG1448 Aspartate/tyrosine/aromatic aminotransferase.
   
 
 0.912
AFY21107.1
[E] COG1448 Aspartate/tyrosine/aromatic aminotransferase.
   
 
 0.912
Your Current Organism:
Pseudomonas sp. UW4
NCBI taxonomy Id: 1207075
Other names: P. sp. UW4
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