node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cdsA | dxr | PputUW4_01093 | PputUW4_01094 | Phosphatidate cytidylyltransferase; [I] COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.937 |
cdsA | fabZ | PputUW4_01093 | PputUW4_01099 | Phosphatidate cytidylyltransferase; [I] COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. | (3R)-hydroxymyristoyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.547 |
cdsA | lpxD | PputUW4_01093 | PputUW4_01098 | Phosphatidate cytidylyltransferase; [I] COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.631 |
cdsA | ompH | PputUW4_01093 | PputUW4_01097 | Phosphatidate cytidylyltransferase; [I] COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. | [M] COG2825 Outer membrane protein. | 0.473 |
cdsA | pyrH | PputUW4_01093 | PputUW4_01090 | Phosphatidate cytidylyltransferase; [I] COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.950 |
cdsA | rrf | PputUW4_01093 | PputUW4_01091 | Phosphatidate cytidylyltransferase; [I] COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.900 |
cdsA | rseP | PputUW4_01093 | PputUW4_01095 | Phosphatidate cytidylyltransferase; [I] COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. | Membrane-associated zinc metalloprotease; [M] COG0750 Predicted membrane-associated Zn-dependent proteases 1. | 0.857 |
cdsA | uppS | PputUW4_01093 | PputUW4_01092 | Phosphatidate cytidylyltransferase; [I] COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. | Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.982 |
cdsA | yaeT | PputUW4_01093 | PputUW4_01096 | Phosphatidate cytidylyltransferase; [I] COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. | Outer membrane protein assembly complex,YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.622 |
dxr | cdsA | PputUW4_01094 | PputUW4_01093 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Phosphatidate cytidylyltransferase; [I] COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. | 0.937 |
dxr | fabZ | PputUW4_01094 | PputUW4_01099 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | (3R)-hydroxymyristoyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.450 |
dxr | lpxD | PputUW4_01094 | PputUW4_01098 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.524 |
dxr | ompH | PputUW4_01094 | PputUW4_01097 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | [M] COG2825 Outer membrane protein. | 0.493 |
dxr | pyrH | PputUW4_01094 | PputUW4_01090 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.851 |
dxr | rrf | PputUW4_01094 | PputUW4_01091 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.877 |
dxr | rseP | PputUW4_01094 | PputUW4_01095 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Membrane-associated zinc metalloprotease; [M] COG0750 Predicted membrane-associated Zn-dependent proteases 1. | 0.820 |
dxr | uppS | PputUW4_01094 | PputUW4_01092 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.974 |
dxr | yaeT | PputUW4_01094 | PputUW4_01096 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Outer membrane protein assembly complex,YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.634 |
fabZ | cdsA | PputUW4_01099 | PputUW4_01093 | (3R)-hydroxymyristoyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | Phosphatidate cytidylyltransferase; [I] COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. | 0.547 |
fabZ | dxr | PputUW4_01099 | PputUW4_01094 | (3R)-hydroxymyristoyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.450 |