STRINGSTRING
AFY18967.1 AFY18967.1 AFY18969.1 AFY18969.1 pycB pycB AFY18968.1 AFY18968.1 AFY18970.1 AFY18970.1 fadB fadB fadJ fadJ accA accA birA birA AFY18682.1 AFY18682.1 AFY18642.1 AFY18642.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
AFY18967.1[I] COG0439 Biotin carboxylase. (651 aa)    
Predicted Functional Partners:
AFY18969.1
[I] COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit.
 0.996
pycB
[C] COG5016 Pyruvate/oxaloacetate carboxyltransferase.
 
0.994
AFY18968.1
[I] COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.
 0.985
AFY18970.1
[I] COG1960 Acyl-CoA dehydrogenases.
 
 0.962
fadB
Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.948
fadJ
3-hydroxyacyl-CoA dehydrogenase/short chain enoyl-CoA hydratase; [I] COG1250 3-hydroxyacyl-CoA dehydrogenase.
  
 0.948
accA
acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 
 0.947
birA
Bifunctional protein biotin operon repressor/ biotin-[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
 0.944
AFY18682.1
[I] COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta).
 0.939
AFY18642.1
[I] COG1024 Enoyl-CoA hydratase/carnithine racemase.
  
 0.928
Your Current Organism:
Pseudomonas sp. UW4
NCBI taxonomy Id: 1207075
Other names: P. sp. UW4
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