node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFY18281.1 | AFY20708.1 | PputUW4_01074 | PputUW4_03515 | Hypothetical protein. | [K] COG1309 Transcriptional regulator. | 0.440 |
AFY18281.1 | AFY21517.1 | PputUW4_01074 | PputUW4_04325 | Hypothetical protein. | DNA binding protein MvaT, H-NS family. | 0.745 |
AFY18281.1 | ompH | PputUW4_01074 | PputUW4_01097 | Hypothetical protein. | [M] COG2825 Outer membrane protein. | 0.752 |
AFY18281.1 | sulA | PputUW4_01074 | PputUW4_03517 | Hypothetical protein. | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 0.698 |
AFY20708.1 | AFY18281.1 | PputUW4_03515 | PputUW4_01074 | [K] COG1309 Transcriptional regulator. | Hypothetical protein. | 0.440 |
AFY20708.1 | AFY21517.1 | PputUW4_03515 | PputUW4_04325 | [K] COG1309 Transcriptional regulator. | DNA binding protein MvaT, H-NS family. | 0.461 |
AFY20708.1 | lexA2 | PputUW4_03515 | PputUW4_03516 | [K] COG1309 Transcriptional regulator. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.544 |
AFY20708.1 | mtnP | PputUW4_03515 | PputUW4_03513 | [K] COG1309 Transcriptional regulator. | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 0.544 |
AFY20708.1 | nagZ | PputUW4_03515 | PputUW4_03514 | [K] COG1309 Transcriptional regulator. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.556 |
AFY20708.1 | ompH | PputUW4_03515 | PputUW4_01097 | [K] COG1309 Transcriptional regulator. | [M] COG2825 Outer membrane protein. | 0.540 |
AFY20708.1 | sulA | PputUW4_03515 | PputUW4_03517 | [K] COG1309 Transcriptional regulator. | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 0.543 |
AFY21517.1 | AFY18281.1 | PputUW4_04325 | PputUW4_01074 | DNA binding protein MvaT, H-NS family. | Hypothetical protein. | 0.745 |
AFY21517.1 | AFY20708.1 | PputUW4_04325 | PputUW4_03515 | DNA binding protein MvaT, H-NS family. | [K] COG1309 Transcriptional regulator. | 0.461 |
AFY21517.1 | ompH | PputUW4_04325 | PputUW4_01097 | DNA binding protein MvaT, H-NS family. | [M] COG2825 Outer membrane protein. | 0.724 |
lexA2 | AFY20708.1 | PputUW4_03516 | PputUW4_03515 | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | [K] COG1309 Transcriptional regulator. | 0.544 |
lexA2 | sulA | PputUW4_03516 | PputUW4_03517 | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 0.893 |
mtnP | AFY20708.1 | PputUW4_03513 | PputUW4_03515 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | [K] COG1309 Transcriptional regulator. | 0.544 |
mtnP | nagZ | PputUW4_03513 | PputUW4_03514 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.797 |
mtnP | sulA | PputUW4_03513 | PputUW4_03517 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 0.408 |
nagZ | AFY20708.1 | PputUW4_03514 | PputUW4_03515 | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | [K] COG1309 Transcriptional regulator. | 0.556 |