STRINGSTRING
sulA sulA lexA2 lexA2 AFY18037.1 AFY18037.1 ftsZ ftsZ recN recN AFY21279.1 AFY21279.1 AFY22121.1 AFY22121.1 damX damX AFY21930.1 AFY21930.1 AFY21253.1 AFY21253.1 phaG1 phaG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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sulASOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. (158 aa)    
Predicted Functional Partners:
lexA2
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
  
 0.893
AFY18037.1
YebG family protein; [S] COG3141 Uncharacterized protein conserved in bacteria.
  
    0.823
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
    
 
 0.822
recN
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
   
  
 0.779
AFY21279.1
Hypothetical protein.
  
     0.759
AFY22121.1
Hypothetical protein.
  
     0.743
damX
Sporulation domain-containing protein; [U] COG3267 Type II secretory pathway, component ExeA (predicted ATPase).
  
     0.741
AFY21930.1
Hypothetical protein.
  
     0.740
AFY21253.1
Hypothetical protein.
  
     0.737
phaG1
(R)-3-hydroxydecanoyl-ACP:CoA transacylase; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
  
     0.734
Your Current Organism:
Pseudomonas sp. UW4
NCBI taxonomy Id: 1207075
Other names: P. sp. UW4
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