STRINGSTRING
AFY20892.1 AFY20892.1 mtnB mtnB mtnC mtnC mtnD mtnD aroC aroC AFY19125.1 AFY19125.1 AFY20894.1 AFY20894.1 AFY20175.1 AFY20175.1 AFY20895.1 AFY20895.1 fruA fruA gltB gltB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AFY20892.1[GEPR] COG0477 Permeases of the major facilitator superfamily. (383 aa)    
Predicted Functional Partners:
mtnB
Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily.
  
  
 0.846
mtnC
2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
     
 0.803
mtnD
Acireductone dioxygenase, ARD; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
     
 0.800
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
     
 0.746
AFY19125.1
Phosphatase; [R] COG0637 Predicted phosphatase/phosphohexomutase.
  
  
 0.644
AFY20894.1
[R] COG1073 Hydrolases of the alpha/beta superfamily.
       0.555
AFY20175.1
Hypothetical protein; [S] COG3496 Uncharacterized conserved protein.
  
  
 0.497
AFY20895.1
Hypothetical protein.
       0.443
fruA
PTS system fructose-specific transporter subunit IIBC; [G] COG1299 Phosphotransferase system, fructose-specific IIC component.
  
  
 0.438
gltB
[E] COG0069 Glutamate synthase domain 2.
     
 0.425
Your Current Organism:
Pseudomonas sp. UW4
NCBI taxonomy Id: 1207075
Other names: P. sp. UW4
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