node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFY20516.1 | bluB | PputUW4_03321 | PputUW4_03773 | YcaO-like fatty acid binding protein; [O] COG1765 Predicted redox protein, regulator of disulfide bond formation. | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | 0.708 |
bluB | AFY20516.1 | PputUW4_03773 | PputUW4_03321 | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | YcaO-like fatty acid binding protein; [O] COG1765 Predicted redox protein, regulator of disulfide bond formation. | 0.708 |
bluB | cobB | PputUW4_03773 | PputUW4_03774 | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.984 |
bluB | cobC2 | PputUW4_03773 | PputUW4_03771 | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | Threonine-phosphate decarboxylase; [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.940 |
bluB | cobD | PputUW4_03773 | PputUW4_03772 | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.927 |
bluB | cobO | PputUW4_03773 | PputUW4_03775 | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.899 |
bluB | cobQ | PputUW4_03773 | PputUW4_03770 | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.912 |
bluB | cobS | PputUW4_03773 | PputUW4_03766 | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.720 |
bluB | cobT | PputUW4_03773 | PputUW4_03768 | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.995 |
bluB | cobU | PputUW4_03773 | PputUW4_03769 | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | Adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.928 |
bluB | ssuE | PputUW4_03773 | PputUW4_05213 | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | NAD(P)H-dependent FMN reductase; [R] COG0431 Predicted flavoprotein. | 0.907 |
cobB | bluB | PputUW4_03774 | PputUW4_03773 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | 0.984 |
cobB | cobC2 | PputUW4_03774 | PputUW4_03771 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Threonine-phosphate decarboxylase; [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.948 |
cobB | cobD | PputUW4_03774 | PputUW4_03772 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.977 |
cobB | cobO | PputUW4_03774 | PputUW4_03775 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.993 |
cobB | cobQ | PputUW4_03774 | PputUW4_03770 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.989 |
cobB | cobS | PputUW4_03774 | PputUW4_03766 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.922 |
cobB | cobT | PputUW4_03774 | PputUW4_03768 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.971 |
cobB | cobU | PputUW4_03774 | PputUW4_03769 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.965 |
cobC2 | bluB | PputUW4_03771 | PputUW4_03773 | Threonine-phosphate decarboxylase; [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | 0.940 |