node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bluB | cobB | PputUW4_03773 | PputUW4_03774 | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.984 |
bluB | cobC2 | PputUW4_03773 | PputUW4_03771 | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | Threonine-phosphate decarboxylase; [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.940 |
bluB | cobD | PputUW4_03773 | PputUW4_03772 | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.927 |
bluB | cobH | PputUW4_03773 | PputUW4_00539 | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | precorrin-8X methylmutase; [H] COG2082 Precorrin isomerase. | 0.587 |
bluB | cobJ | PputUW4_03773 | PputUW4_00541 | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | [H] COG1010 Precorrin-3B methylase. | 0.616 |
bluB | cobN | PputUW4_03773 | PputUW4_02362 | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | Cobaltochelatase subunit CobN; [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases. | 0.641 |
bluB | cobO | PputUW4_03773 | PputUW4_03775 | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.899 |
bluB | cobQ | PputUW4_03773 | PputUW4_03770 | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.912 |
bluB | cobT | PputUW4_03773 | PputUW4_03768 | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.995 |
bluB | cobU | PputUW4_03773 | PputUW4_03769 | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | Adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.928 |
cobB | bluB | PputUW4_03774 | PputUW4_03773 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | cob(II)yrinic acid a,c-diamide reductase; [C] COG0778 Nitroreductase. | 0.984 |
cobB | cobC2 | PputUW4_03774 | PputUW4_03771 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Threonine-phosphate decarboxylase; [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.948 |
cobB | cobD | PputUW4_03774 | PputUW4_03772 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.977 |
cobB | cobH | PputUW4_03774 | PputUW4_00539 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | precorrin-8X methylmutase; [H] COG2082 Precorrin isomerase. | 0.994 |
cobB | cobJ | PputUW4_03774 | PputUW4_00541 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | [H] COG1010 Precorrin-3B methylase. | 0.951 |
cobB | cobN | PputUW4_03774 | PputUW4_02362 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobaltochelatase subunit CobN; [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases. | 0.982 |
cobB | cobO | PputUW4_03774 | PputUW4_03775 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.993 |
cobB | cobQ | PputUW4_03774 | PputUW4_03770 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.989 |
cobB | cobT | PputUW4_03774 | PputUW4_03768 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.971 |
cobB | cobU | PputUW4_03774 | PputUW4_03769 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.965 |