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cycH cycH ccmF ccmF dsbE2 dsbE2 ccmH ccmH ccmE ccmE ccmC ccmC ccmB ccmB ccmA ccmA ccmD ccmD AFY21023.1 AFY21023.1 AFY17533.1 AFY17533.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cycH[O] COG4235 Cytochrome c biogenesis factor. (400 aa)    
Predicted Functional Partners:
ccmF
[O] COG1138 Cytochrome c biogenesis factor.
 
 
 0.990
dsbE2
Thiol:disulfide interchange protein; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins.
 
  
 0.983
ccmH
Cytochrome C biogenesis protein; Possible subunit of a heme lyase.
 
  
 0.979
ccmE
Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
  
 0.967
ccmC
Cytochrome c-type biogenesis protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
  
 0.960
ccmB
Cytochrome c-type biogenesis protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 
   
 0.922
ccmA
Cytochrome c biogenesis protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 
   
 0.910
ccmD
Cytochrome c-type biogenesis protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.
 
  
 0.901
AFY21023.1
Hypothetical protein.
  
    0.785
AFY17533.1
Sterol-binding domain-containing protein; [S] COG3165 Uncharacterized protein conserved in bacteria.
  
    0.603
Your Current Organism:
Pseudomonas sp. UW4
NCBI taxonomy Id: 1207075
Other names: P. sp. UW4
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