node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFY17926.1 | mgtE | PputUW4_00719 | PputUW4_04162 | [G] COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria); Belongs to the PEP-utilizing enzyme family. | Magnesium transporter; Acts as a magnesium transporter. | 0.559 |
AFY20356.1 | guaA1 | PputUW4_03161 | PputUW4_00980 | Cystathionine beta-synthase; [E] COG0031 Cysteine synthase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.544 |
AFY20356.1 | mgtE | PputUW4_03161 | PputUW4_04162 | Cystathionine beta-synthase; [E] COG0031 Cysteine synthase. | Magnesium transporter; Acts as a magnesium transporter. | 0.478 |
glmS | guaA1 | PputUW4_05423 | PputUW4_00980 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.609 |
glmS | mgtE | PputUW4_05423 | PputUW4_04162 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Magnesium transporter; Acts as a magnesium transporter. | 0.522 |
glmS | moaA1 | PputUW4_05423 | PputUW4_03057 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.441 |
guaA1 | AFY20356.1 | PputUW4_00980 | PputUW4_03161 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Cystathionine beta-synthase; [E] COG0031 Cysteine synthase. | 0.544 |
guaA1 | glmS | PputUW4_00980 | PputUW4_05423 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.609 |
guaA1 | ilvC | PputUW4_00980 | PputUW4_04611 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.464 |
guaA1 | mgtE | PputUW4_00980 | PputUW4_04162 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Magnesium transporter; Acts as a magnesium transporter. | 0.464 |
ilvC | guaA1 | PputUW4_04611 | PputUW4_00980 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.464 |
ilvC | mgtE | PputUW4_04611 | PputUW4_04162 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Magnesium transporter; Acts as a magnesium transporter. | 0.415 |
ilvC | moaA1 | PputUW4_04611 | PputUW4_03057 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.532 |
mgtE | AFY17926.1 | PputUW4_04162 | PputUW4_00719 | Magnesium transporter; Acts as a magnesium transporter. | [G] COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria); Belongs to the PEP-utilizing enzyme family. | 0.559 |
mgtE | AFY20356.1 | PputUW4_04162 | PputUW4_03161 | Magnesium transporter; Acts as a magnesium transporter. | Cystathionine beta-synthase; [E] COG0031 Cysteine synthase. | 0.478 |
mgtE | glmS | PputUW4_04162 | PputUW4_05423 | Magnesium transporter; Acts as a magnesium transporter. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.522 |
mgtE | guaA1 | PputUW4_04162 | PputUW4_00980 | Magnesium transporter; Acts as a magnesium transporter. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.464 |
mgtE | ilvC | PputUW4_04162 | PputUW4_04611 | Magnesium transporter; Acts as a magnesium transporter. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.415 |
mgtE | moaA1 | PputUW4_04162 | PputUW4_03057 | Magnesium transporter; Acts as a magnesium transporter. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.478 |
moaA1 | glmS | PputUW4_03057 | PputUW4_05423 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.441 |