STRINGSTRING
panE2 panE2 panE1 panE1 panB panB panC panC AFY21504.1 AFY21504.1 AFY21503.1 AFY21503.1 AFY21501.1 AFY21501.1 alkB alkB birA birA mscS3 mscS3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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panE22-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (305 aa)    
Predicted Functional Partners:
panE1
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
  
  
  0.966
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.924
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
    
 0.924
AFY21504.1
ATP:cob(I)alamin adenosyltransferase; [S] COG2096 Uncharacterized conserved protein; Belongs to the Cob(I)alamin adenosyltransferase family.
       0.671
AFY21503.1
[T] COG0642 Signal transduction histidine kinase.
       0.664
AFY21501.1
[S] COG1666 Uncharacterized protein conserved in bacteria; Belongs to the UPF0234 family.
       0.597
alkB
[L] COG3145 Alkylated DNA repair protein.
   
    0.591
birA
Bifunctional protein biotin operon repressor/ biotin-[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
 
   
 0.504
mscS3
[M] COG0668 Small-conductance mechanosensitive channel.
       0.452
Your Current Organism:
Pseudomonas sp. UW4
NCBI taxonomy Id: 1207075
Other names: P. sp. UW4
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