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pyk2 pyk2 eno eno pgi pgi pycB pycB maeB maeB gmk gmk ldhA ldhA pckA pckA aceE1 aceE1 aceE2 aceE2 adk adk
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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pyk2[G] COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. (483 aa)    
Predicted Functional Partners:
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
 
 0.981
pgi
[G] COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family.
 
 
 0.962
pycB
[C] COG5016 Pyruvate/oxaloacetate carboxyltransferase.
  
 
 0.949
maeB
[C] COG0281 Malic enzyme.
  
 0.941
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
 
 0.932
ldhA
[CHR] COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.929
pckA
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
    
 0.919
aceE1
Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.919
aceE2
Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.919
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 0.918
Your Current Organism:
Pseudomonas sp. UW4
NCBI taxonomy Id: 1207075
Other names: P. sp. UW4
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