node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFY18852.1 | aroA | PputUW4_01647 | PputUW4_01362 | [E] COG0169 Shikimate 5-dehydrogenase. | Bifunctional cyclohexadienyldehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.816 |
AFY18852.1 | aroB | PputUW4_01647 | PputUW4_00350 | [E] COG0169 Shikimate 5-dehydrogenase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.446 |
AFY18852.1 | aroC | PputUW4_01647 | PputUW4_03701 | [E] COG0169 Shikimate 5-dehydrogenase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.620 |
AFY18852.1 | aroE1 | PputUW4_01647 | PputUW4_00022 | [E] COG0169 Shikimate 5-dehydrogenase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.910 |
AFY18852.1 | aroE2 | PputUW4_01647 | PputUW4_04721 | [E] COG0169 Shikimate 5-dehydrogenase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.922 |
AFY18852.1 | aroK | PputUW4_01647 | PputUW4_00349 | [E] COG0169 Shikimate 5-dehydrogenase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.956 |
AFY18852.1 | aroQ1 | PputUW4_01647 | PputUW4_00554 | [E] COG0169 Shikimate 5-dehydrogenase. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.916 |
AFY18852.1 | aroQ2 | PputUW4_01647 | PputUW4_04720 | [E] COG0169 Shikimate 5-dehydrogenase. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.927 |
AFY18852.1 | quiA | PputUW4_01647 | PputUW4_04960 | [E] COG0169 Shikimate 5-dehydrogenase. | [G] COG4993 Glucose dehydrogenase. | 0.900 |
AFY21913.1 | aroA | PputUW4_04723 | PputUW4_01362 | [ER] COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins. | Bifunctional cyclohexadienyldehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.490 |
AFY21913.1 | aroE2 | PputUW4_04723 | PputUW4_04721 | [ER] COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.817 |
aroA | AFY18852.1 | PputUW4_01362 | PputUW4_01647 | Bifunctional cyclohexadienyldehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | [E] COG0169 Shikimate 5-dehydrogenase. | 0.816 |
aroA | AFY21913.1 | PputUW4_01362 | PputUW4_04723 | Bifunctional cyclohexadienyldehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | [ER] COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins. | 0.490 |
aroA | aroB | PputUW4_01362 | PputUW4_00350 | Bifunctional cyclohexadienyldehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.996 |
aroA | aroC | PputUW4_01362 | PputUW4_03701 | Bifunctional cyclohexadienyldehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.997 |
aroA | aroE1 | PputUW4_01362 | PputUW4_00022 | Bifunctional cyclohexadienyldehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.874 |
aroA | aroE2 | PputUW4_01362 | PputUW4_04721 | Bifunctional cyclohexadienyldehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.833 |
aroA | aroK | PputUW4_01362 | PputUW4_00349 | Bifunctional cyclohexadienyldehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.988 |
aroA | aroQ1 | PputUW4_01362 | PputUW4_00554 | Bifunctional cyclohexadienyldehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.584 |
aroA | aroQ2 | PputUW4_01362 | PputUW4_04720 | Bifunctional cyclohexadienyldehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.581 |