node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFY21986.1 | acoR | PputUW4_04796 | PputUW4_04799 | Lipoprotein; [R] COG5645 Predicted periplasmic lipoprotein. | Sigma54 specific transcriptional regulator; [QK] COG3284 Transcriptional activator of acetoin/glycerol metabolism. | 0.513 |
AFY21986.1 | mpl | PputUW4_04796 | PputUW4_04798 | Lipoprotein; [R] COG5645 Predicted periplasmic lipoprotein. | UDP-N-acetylmuramate; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.807 |
AFY21986.1 | ubiX | PputUW4_04796 | PputUW4_04797 | Lipoprotein; [R] COG5645 Predicted periplasmic lipoprotein. | Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.807 |
AFY22422.1 | ispB | PputUW4_05233 | PputUW4_04677 | [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | [H] COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.443 |
AFY22422.1 | ubiA | PputUW4_05233 | PputUW4_05352 | [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.755 |
AFY22422.1 | ubiD | PputUW4_05233 | PputUW4_05248 | [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | 0.916 |
AFY22422.1 | ubiX | PputUW4_05233 | PputUW4_04797 | [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.916 |
AFY22456.1 | ubiD | PputUW4_05267 | PputUW4_05248 | Hypothetical protein; [S] COG5589 Uncharacterized conserved protein. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | 0.435 |
AFY22456.1 | ubiX | PputUW4_05267 | PputUW4_04797 | Hypothetical protein; [S] COG5589 Uncharacterized conserved protein. | Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.442 |
acoR | AFY21986.1 | PputUW4_04799 | PputUW4_04796 | Sigma54 specific transcriptional regulator; [QK] COG3284 Transcriptional activator of acetoin/glycerol metabolism. | Lipoprotein; [R] COG5645 Predicted periplasmic lipoprotein. | 0.513 |
acoR | mpl | PputUW4_04799 | PputUW4_04798 | Sigma54 specific transcriptional regulator; [QK] COG3284 Transcriptional activator of acetoin/glycerol metabolism. | UDP-N-acetylmuramate; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.513 |
acoR | ubiX | PputUW4_04799 | PputUW4_04797 | Sigma54 specific transcriptional regulator; [QK] COG3284 Transcriptional activator of acetoin/glycerol metabolism. | Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.513 |
ispB | AFY22422.1 | PputUW4_04677 | PputUW4_05233 | [H] COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.443 |
ispB | ispE | PputUW4_04677 | PputUW4_04581 | [H] COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.411 |
ispB | ubiA | PputUW4_04677 | PputUW4_05352 | [H] COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.909 |
ispB | ubiX | PputUW4_04677 | PputUW4_04797 | [H] COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.427 |
ispE | ispB | PputUW4_04581 | PputUW4_04677 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | [H] COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.411 |
ispE | ubiX | PputUW4_04581 | PputUW4_04797 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.421 |
mpl | AFY21986.1 | PputUW4_04798 | PputUW4_04796 | UDP-N-acetylmuramate; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | Lipoprotein; [R] COG5645 Predicted periplasmic lipoprotein. | 0.807 |
mpl | acoR | PputUW4_04798 | PputUW4_04799 | UDP-N-acetylmuramate; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | Sigma54 specific transcriptional regulator; [QK] COG3284 Transcriptional activator of acetoin/glycerol metabolism. | 0.513 |