node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFY19090.1 | aroC | PputUW4_01885 | PputUW4_03701 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.967 |
AFY19090.1 | pabB | PputUW4_01885 | PputUW4_03663 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. | Aminodeoxychorismate synthase, subunit I; [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I. | 0.836 |
AFY19090.1 | pheA | PputUW4_01885 | PputUW4_01360 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. | Chorismate mutase/prephenate dehydrogenase; [E] COG0077 Prephenate dehydratase. | 0.926 |
AFY19090.1 | trpE | PputUW4_01885 | PputUW4_04921 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.918 |
AFY19090.1 | trpG | PputUW4_01885 | PputUW4_04919 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. | [E] COG0512 Anthranilate/para-aminobenzoate synthases component II. | 0.924 |
aroC | AFY19090.1 | PputUW4_03701 | PputUW4_01885 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. | 0.967 |
aroC | pabB | PputUW4_03701 | PputUW4_03663 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Aminodeoxychorismate synthase, subunit I; [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I. | 0.944 |
aroC | pheA | PputUW4_03701 | PputUW4_01360 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Chorismate mutase/prephenate dehydrogenase; [E] COG0077 Prephenate dehydratase. | 0.984 |
aroC | trpA | PputUW4_03701 | PputUW4_00096 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.843 |
aroC | trpB | PputUW4_03701 | PputUW4_00095 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.733 |
aroC | trpC | PputUW4_03701 | PputUW4_04917 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | [E] COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.653 |
aroC | trpD | PputUW4_03701 | PputUW4_04918 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.703 |
aroC | trpE | PputUW4_03701 | PputUW4_04921 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.971 |
aroC | trpF | PputUW4_03701 | PputUW4_03442 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | [E] COG0135 Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.546 |
aroC | trpG | PputUW4_03701 | PputUW4_04919 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | [E] COG0512 Anthranilate/para-aminobenzoate synthases component II. | 0.974 |
pabB | AFY19090.1 | PputUW4_03663 | PputUW4_01885 | Aminodeoxychorismate synthase, subunit I; [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I. | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. | 0.836 |
pabB | aroC | PputUW4_03663 | PputUW4_03701 | Aminodeoxychorismate synthase, subunit I; [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.944 |
pabB | pheA | PputUW4_03663 | PputUW4_01360 | Aminodeoxychorismate synthase, subunit I; [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I. | Chorismate mutase/prephenate dehydrogenase; [E] COG0077 Prephenate dehydratase. | 0.901 |
pabB | trpA | PputUW4_03663 | PputUW4_00096 | Aminodeoxychorismate synthase, subunit I; [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.931 |
pabB | trpB | PputUW4_03663 | PputUW4_00095 | Aminodeoxychorismate synthase, subunit I; [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.944 |