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folK2 folK2 folB folB folP folP folK1 folK1 folX folX folE1 folE1 folE2 folE2 ribD ribD plsY plsY birA birA AFY20633.1 AFY20633.1
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query proteins and first shell of interactors
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second shell of interactors
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Predicted Interactions
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textmining
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Score
folK22-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. (172 aa)    
Predicted Functional Partners:
folB
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 
 0.994
folP
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 
 0.991
folK1
[H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.
  
  
 
0.924
folX
D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase; [H] COG1539 Dihydroneopterin aldolase.
 
  
 0.756
folE1
[H] COG0302 GTP cyclohydrolase I.
 
  
 0.752
folE2
[H] COG0302 GTP cyclohydrolase I.
 
  
 0.752
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 
  
 0.680
plsY
Glycerol-3-phosphate acyltransferase PlsY; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
  
  
 0.653
birA
Bifunctional protein biotin operon repressor/ biotin-[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
 
  
 0.609
AFY20633.1
[H] COG0285 Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.
  
  
 0.505
Your Current Organism:
Pseudomonas sp. UW4
NCBI taxonomy Id: 1207075
Other names: P. sp. UW4
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