node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFY21035.1 | gcvP1 | PputUW4_03843 | PputUW4_04281 | Sarcosine oxidase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.911 |
AFY21035.1 | glyA1 | PputUW4_03843 | PputUW4_01863 | Sarcosine oxidase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.907 |
AFY21035.1 | glyA2 | PputUW4_03843 | PputUW4_04696 | Sarcosine oxidase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.907 |
AFY21035.1 | glyA3 | PputUW4_03843 | PputUW4_05012 | Sarcosine oxidase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.907 |
AFY21035.1 | ltaE | PputUW4_03843 | PputUW4_05014 | Sarcosine oxidase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.900 |
AFY21035.1 | soxA | PputUW4_03843 | PputUW4_05009 | Sarcosine oxidase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | Sarcosine oxidase, alpha subunit; [E] COG0404 Glycine cleavage system T protein (aminomethyltransferase); Belongs to the GcvT family. | 0.971 |
AFY21035.1 | soxB | PputUW4_03843 | PputUW4_05011 | Sarcosine oxidase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | Sarcosine oxidase, beta subunit; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.900 |
AFY21035.1 | soxD | PputUW4_03843 | PputUW4_05010 | Sarcosine oxidase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | [E] COG4311 Sarcosine oxidase delta subunit. | 0.943 |
AFY21035.1 | soxG | PputUW4_03843 | PputUW4_05008 | Sarcosine oxidase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | [E] COG4583 Sarcosine oxidase gamma subunit. | 0.933 |
AFY22215.1 | gcvP1 | PputUW4_05025 | PputUW4_04281 | NADH:flavin oxidoreductase/NADH oxidase; [C] COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.426 |
AFY22215.1 | soxA | PputUW4_05025 | PputUW4_05009 | NADH:flavin oxidoreductase/NADH oxidase; [C] COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Sarcosine oxidase, alpha subunit; [E] COG0404 Glycine cleavage system T protein (aminomethyltransferase); Belongs to the GcvT family. | 0.753 |
AFY22215.1 | soxB | PputUW4_05025 | PputUW4_05011 | NADH:flavin oxidoreductase/NADH oxidase; [C] COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Sarcosine oxidase, beta subunit; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.881 |
AFY22215.1 | soxD | PputUW4_05025 | PputUW4_05010 | NADH:flavin oxidoreductase/NADH oxidase; [C] COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | [E] COG4311 Sarcosine oxidase delta subunit. | 0.945 |
AFY22215.1 | soxG | PputUW4_05025 | PputUW4_05008 | NADH:flavin oxidoreductase/NADH oxidase; [C] COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | [E] COG4583 Sarcosine oxidase gamma subunit. | 0.949 |
gcvP1 | AFY21035.1 | PputUW4_04281 | PputUW4_03843 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Sarcosine oxidase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.911 |
gcvP1 | AFY22215.1 | PputUW4_04281 | PputUW4_05025 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | NADH:flavin oxidoreductase/NADH oxidase; [C] COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.426 |
gcvP1 | glyA1 | PputUW4_04281 | PputUW4_01863 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.985 |
gcvP1 | glyA2 | PputUW4_04281 | PputUW4_04696 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.985 |
gcvP1 | glyA3 | PputUW4_04281 | PputUW4_05012 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.985 |
gcvP1 | ltaE | PputUW4_04281 | PputUW4_05014 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.944 |