soxA protein (Pseudomonas sp. UW4) - STRING interaction network

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Score

soxA

Sarcosine oxidase, alpha subunit; [E] COG0404 Glycine cleavage system T protein (aminomethyltransferase); Belongs to the GcvT family. (1005 aa)

Predicted Functional Partners:

soxG

0.999

soxD

0.999

soxB

0.998

gcvP1

0.996

gcvP2

0.996

glyA3

0.988

AFY21035.1

0.971

glyA1

0.965

glyA2

0.965

ltaE

0.937

Your Current Organism:

Pseudomonas sp. UW4

NCBI taxonomy Id: 1207075
Other names: P. sp. UW4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFY21035.1	gcvP1	PputUW4_03843	PputUW4_04281	Sarcosine oxidase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating).	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	0.911
AFY21035.1	gcvP2	PputUW4_03843	PputUW4_05228	Sarcosine oxidase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating).	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	0.911
AFY21035.1	glyA1	PputUW4_03843	PputUW4_01863	Sarcosine oxidase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating).	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.907
AFY21035.1	glyA2	PputUW4_03843	PputUW4_04696	Sarcosine oxidase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating).	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.907
AFY21035.1	glyA3	PputUW4_03843	PputUW4_05012	Sarcosine oxidase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating).	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.907
AFY21035.1	ltaE	PputUW4_03843	PputUW4_05014	Sarcosine oxidase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating).	L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.	0.900
AFY21035.1	soxA	PputUW4_03843	PputUW4_05009	Sarcosine oxidase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating).	Sarcosine oxidase, alpha subunit; [E] COG0404 Glycine cleavage system T protein (aminomethyltransferase); Belongs to the GcvT family.	0.971
AFY21035.1	soxB	PputUW4_03843	PputUW4_05011	Sarcosine oxidase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating).	Sarcosine oxidase, beta subunit; [E] COG0665 Glycine/D-amino acid oxidases (deaminating).	0.900
AFY21035.1	soxD	PputUW4_03843	PputUW4_05010	Sarcosine oxidase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating).	[E] COG4311 Sarcosine oxidase delta subunit.	0.943
AFY21035.1	soxG	PputUW4_03843	PputUW4_05008	Sarcosine oxidase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating).	[E] COG4583 Sarcosine oxidase gamma subunit.	0.933
gcvP1	AFY21035.1	PputUW4_04281	PputUW4_03843	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Sarcosine oxidase; [E] COG0665 Glycine/D-amino acid oxidases (deaminating).	0.911
gcvP1	gcvP2	PputUW4_04281	PputUW4_05228	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	0.999
gcvP1	glyA1	PputUW4_04281	PputUW4_01863	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.985
gcvP1	glyA2	PputUW4_04281	PputUW4_04696	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.985
gcvP1	glyA3	PputUW4_04281	PputUW4_05012	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.985
gcvP1	ltaE	PputUW4_04281	PputUW4_05014	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.	0.944
gcvP1	soxA	PputUW4_04281	PputUW4_05009	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Sarcosine oxidase, alpha subunit; [E] COG0404 Glycine cleavage system T protein (aminomethyltransferase); Belongs to the GcvT family.	0.996
gcvP1	soxB	PputUW4_04281	PputUW4_05011	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Sarcosine oxidase, beta subunit; [E] COG0665 Glycine/D-amino acid oxidases (deaminating).	0.911
gcvP1	soxD	PputUW4_04281	PputUW4_05010	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	[E] COG4311 Sarcosine oxidase delta subunit.	0.905
gcvP1	soxG	PputUW4_04281	PputUW4_05008	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	[E] COG4583 Sarcosine oxidase gamma subunit.	0.912