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ahcY ahcY metE metE metH metH AFY20356.1 AFY20356.1 AFY19844.1 AFY19844.1 metZ metZ AFY21380.1 AFY21380.1 AFY19750.1 AFY19750.1 AFY18384.1 AFY18384.1 cysK cysK AFY20357.1 AFY20357.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ahcYS-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (469 aa)    
Predicted Functional Partners:
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.974
metH
B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.959
AFY20356.1
Cystathionine beta-synthase; [E] COG0031 Cysteine synthase.
  
 0.940
AFY19844.1
[E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
  
 0.924
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 0.924
AFY21380.1
Cytosine-specific methyltransferase; [L] COG0270 Site-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
    
 0.912
AFY19750.1
Aminotransferase; [E] COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities.
     
  0.900
AFY18384.1
[E] COG0031 Cysteine synthase.
  
 0.853
cysK
[E] COG0031 Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.853
AFY20357.1
[E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
  
 0.848
Your Current Organism:
Pseudomonas sp. UW4
NCBI taxonomy Id: 1207075
Other names: P. sp. UW4
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