STRINGSTRING
mdcE mdcE mdcD mdcD mdcA mdcA mdcG mdcG mdcC mdcC mdcH mdcH mdcB mdcB accA accA madL madL madM madM pycB pycB
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
mdcEMalonate decarboxylase, gamma subunit. (267 aa)    
Predicted Functional Partners:
mdcD
[I] COG0777 Acetyl-CoA carboxylase beta subunit.
 0.999
mdcA
Malonate decarboxylase, alpha subunit.
 
 
 0.988
mdcG
phosphoribosyl-dephospho-CoA transferase; Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme-A to the apo-[acyl-carrier-protein] of the malonate decarboxylase to yield holo-[acyl-carrier-protein]; Belongs to the MdcG family.
 
  
 0.983
mdcC
Malonate decarboxylase subunit delta; Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.
 
  
 0.975
mdcH
Acyl-carrier-protein S-malonyltransferase; [Q] COG3321 Polyketide synthase modules and related proteins.
 
  
 0.970
mdcB
triphosphoribosyl-dephospho-CoA synthase; Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase; Belongs to the CitG/MdcB family.
 
  
 0.964
accA
acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
  
 
 0.904
madL
Malonate transporter MadL subunit.
 
    0.899
madM
Malonate transporter, MadM subunit.
 
   
 0.892
pycB
[C] COG5016 Pyruvate/oxaloacetate carboxyltransferase.
  
 
 0.788
Your Current Organism:
Pseudomonas sp. UW4
NCBI taxonomy Id: 1207075
Other names: P. sp. UW4
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