STRINGSTRING
mdcA mdcA mdcE mdcE mdcD mdcD mdcC mdcC mdcG mdcG mdcB mdcB mdcH mdcH madL madL madM madM accD accD AFY22280.1 AFY22280.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
mdcAMalonate decarboxylase, alpha subunit. (556 aa)    
Predicted Functional Partners:
mdcE
Malonate decarboxylase, gamma subunit.
 
 
 0.988
mdcD
[I] COG0777 Acetyl-CoA carboxylase beta subunit.
 
 
 0.984
mdcC
Malonate decarboxylase subunit delta; Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.
 
  
 0.980
mdcG
phosphoribosyl-dephospho-CoA transferase; Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme-A to the apo-[acyl-carrier-protein] of the malonate decarboxylase to yield holo-[acyl-carrier-protein]; Belongs to the MdcG family.
 
  
 0.973
mdcB
triphosphoribosyl-dephospho-CoA synthase; Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase; Belongs to the CitG/MdcB family.
  
 0.972
mdcH
Acyl-carrier-protein S-malonyltransferase; [Q] COG3321 Polyketide synthase modules and related proteins.
 
  
 0.946
madL
Malonate transporter MadL subunit.
 
  
 0.905
madM
Malonate transporter, MadM subunit.
 
     0.889
accD
acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
  
 
 0.715
AFY22280.1
[K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.706
Your Current Organism:
Pseudomonas sp. UW4
NCBI taxonomy Id: 1207075
Other names: P. sp. UW4
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