STRINGSTRING
AFY22312.1 AFY22312.1 metW metW rdgB rdgB hemN2 hemN2 AFY22315.1 AFY22315.1 metX metX AFY20759.1 AFY20759.1 AFY22495.1 AFY22495.1 AFY17766.1 AFY17766.1 AFY17455.1 AFY17455.1 AFY22308.1 AFY22308.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFY22312.1Hypothetical protein. (144 aa)    
Predicted Functional Partners:
metW
Methionine biosynthesis protein MetW; [QR] COG0500 SAM-dependent methyltransferases.
     0.923
rdgB
Deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
    0.897
hemN2
Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
       0.807
AFY22315.1
Hypothetical protein.
       0.797
metX
Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
       0.732
AFY20759.1
[S] COG3198 Uncharacterized protein conserved in bacteria.
  
     0.666
AFY22495.1
[C] COG3245 Cytochrome c5.
  
     0.609
AFY17766.1
Hypothetical protein.
  
     0.585
AFY17455.1
Hypothetical protein.
  
     0.582
AFY22308.1
Hypothetical protein; [S] COG0762 Predicted integral membrane protein.
 
     0.582
Your Current Organism:
Pseudomonas sp. UW4
NCBI taxonomy Id: 1207075
Other names: P. sp. UW4
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