STRINGSTRING
cya cya cpdA cpdA pyk1 pyk1 pyk2 pyk2 relA relA AFY22525.1 AFY22525.1 mazG mazG ndk ndk folE1 folE1 ribBA1 ribBA1 moaA1 moaA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
cya[F] COG3072 Adenylate cyclase. (947 aa)    
Predicted Functional Partners:
cpdA
Metallophosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
  
  
 0.964
pyk1
[G] COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.904
pyk2
[G] COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.904
relA
GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
 0.903
AFY22525.1
(p)ppGpp synthetase I SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
 0.903
mazG
Nucleoside triphosphate pyrophosphohydrolase; [R] COG1694 Predicted pyrophosphatase.
     
 0.901
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.900
folE1
[H] COG0302 GTP cyclohydrolase I.
     
  0.800
ribBA1
Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; [H] COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase; In the N-terminal section; belongs to the DHBP synthase family.
     
  0.800
moaA1
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
     
  0.800
Your Current Organism:
Pseudomonas sp. UW4
NCBI taxonomy Id: 1207075
Other names: P. sp. UW4
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