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pyrE pyrE pyrF pyrF pyrD2 pyrD2 carB carB pyrB pyrB carA carA prs prs AFY22300.1 AFY22300.1 benC benC AFY21530.1 AFY21530.1 AFY22436.1 AFY22436.1
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (214 aa)    
Predicted Functional Partners:
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.992
pyrD2
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 0.983
carB
[E] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family.
  
 
 0.935
pyrB
[F] COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.928
carA
[E] COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family.
  
  
 0.919
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 
 0.875
AFY22300.1
[F] COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase.
  
  
 0.848
benC
Benzoate 1,2-dioxygenase ferredoxin reductase subunit; [HC] COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases.
  
  
 0.818
AFY21530.1
Oxidoreductase; [HC] COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases.
  
  
 0.818
AFY22436.1
[HC] COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases.
  
  
 0.818
Your Current Organism:
Pseudomonas sp. UW4
NCBI taxonomy Id: 1207075
Other names: P. sp. UW4
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