node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
carB | purC | PputUW4_00694 | PputUW4_01290 | [E] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | 0.541 |
carB | purD | PputUW4_00694 | PputUW4_00546 | [E] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | [F] COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.761 |
carB | purE | PputUW4_00694 | PputUW4_05371 | [E] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.866 |
carB | purF | PputUW4_00694 | PputUW4_03437 | [E] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.986 |
carB | purH | PputUW4_00694 | PputUW4_00547 | [E] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; [F] COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.672 |
carB | purK | PputUW4_00694 | PputUW4_05370 | [E] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.425 |
carB | purL | PputUW4_00694 | PputUW4_00963 | [E] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.679 |
carB | purM | PputUW4_00694 | PputUW4_03784 | [E] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | [F] COG0150 Phosphoribosylaminoimidazole (AIR) synthetase. | 0.739 |
carB | purN | PputUW4_00694 | PputUW4_03785 | [E] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.564 |
purC | carB | PputUW4_01290 | PputUW4_00694 | [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | [E] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.541 |
purC | purD | PputUW4_01290 | PputUW4_00546 | [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | [F] COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.983 |
purC | purE | PputUW4_01290 | PputUW4_05371 | [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
purC | purF | PputUW4_01290 | PputUW4_03437 | [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.968 |
purC | purH | PputUW4_01290 | PputUW4_00547 | [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; [F] COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.982 |
purC | purK | PputUW4_01290 | PputUW4_05370 | [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.994 |
purC | purL | PputUW4_01290 | PputUW4_00963 | [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.999 |
purC | purM | PputUW4_01290 | PputUW4_03784 | [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | [F] COG0150 Phosphoribosylaminoimidazole (AIR) synthetase. | 0.980 |
purC | purN | PputUW4_01290 | PputUW4_03785 | [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.977 |
purC | purT | PputUW4_01290 | PputUW4_00977 | [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.731 |
purD | carB | PputUW4_00546 | PputUW4_00694 | [F] COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | [E] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.761 |