STRINGSTRING
pycB pycB pycA pycA accC accC AFY18679.1 AFY18679.1 AFY18967.1 AFY18967.1 uca uca AFY18068.1 AFY18068.1 pckA pckA ppsA ppsA pyk1 pyk1 pyk2 pyk2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
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[Homology]
Score
pycB[C] COG5016 Pyruvate/oxaloacetate carboxyltransferase. (602 aa)    
Predicted Functional Partners:
pycA
[C] COG1038 Pyruvate carboxylase.
 0.999
accC
acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 0.995
AFY18679.1
[I] COG0439 Biotin carboxylase.
 
0.994
AFY18967.1
[I] COG0439 Biotin carboxylase.
 
0.994
uca
[I] COG0439 Biotin carboxylase.
 
 
 0.991
AFY18068.1
Hypothetical protein.
  
 
 0.953
pckA
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
    
 0.952
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
  
 
 0.952
pyk1
[G] COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.949
pyk2
[G] COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.949
Your Current Organism:
Pseudomonas sp. UW4
NCBI taxonomy Id: 1207075
Other names: P. sp. UW4
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