STRINGSTRING
glnE glnE glnD glnD ACA70923.1 ACA70923.1 ACA75337.1 ACA75337.1 ACA70896.1 ACA70896.1 ACA70744.1 ACA70744.1 argA argA aroA aroA ACA74321.1 ACA74321.1 ACA75332.1 ACA75332.1 ACA75333.1 ACA75333.1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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glnE(Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...] (977 aa)    
Predicted Functional Partners:
glnD
UTP-GlnB uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
 
   
 0.827
ACA70923.1
TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: pfl:PFL_0386 glutamine synthetase, type I.
 
  
 0.780
ACA75337.1
TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: glycosyl transferase family 9; KEGG: pen:PSEEN5142 ADP-heptose; LPS heptosyl transferase I.
      0.731
ACA70896.1
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: pen:PSEEN0337 glutamate synthase [NADPH] large chain precursor (GOGAT).
     
 0.634
ACA70744.1
PFAM: nitrogen regulatory protein P-II; KEGG: pen:PSEEN5376 nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
 
 
 0.591
argA
TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; KEGG: pen:PSEEN5300 N-alpha-acetylglutamate synthase (amino-acid acetyltransferase).
 
   
 0.582
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
      
 0.581
ACA74321.1
KEGG: pen:PSEEN3969 ATP-dependent helicase; TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase domain protein; helicase-associated domain protein; protein of unknown function DUF1605; SMART: AAA ATPase; DEAD-like helicases.
  
   
 0.554
ACA75332.1
KEGG: pen:PSEEN5137 hypothetical protein.
       0.542
ACA75333.1
PFAM: lipopolysaccharide kinase; KEGG: pen:PSEEN5138 heptose kinase WapQ.
       0.542
Your Current Organism:
Pseudomonas putida W619
NCBI taxonomy Id: 390235
Other names: P. putida W619, Pseudomonas putida str. W619, Pseudomonas putida strain W619
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