node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEF20160.1 | coaD | Psefu_0174 | Psefu_0170 | Methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.874 |
AEF20277.1 | coaD | Psefu_0293 | Psefu_0170 | KEGG: pmy:Pmen_4387 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00255; PFAM: YicC-like, N-terminal; Domain of unknown function DUF1732. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.724 |
AEF20716.1 | AEF24256.1 | Psefu_0738 | Psefu_4304 | Riboflavin biosynthesis protein RibF; SMART: Riboflavin kinase; TIGRFAM: Riboflavin kinase/FAD synthetase; KEGG: pmy:Pmen_0952 bifunctional riboflavin kinase/FMN adenylyltransferase; PFAM: FAD synthetase; Riboflavin kinase; Belongs to the ribF family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.677 |
AEF20716.1 | coaD | Psefu_0738 | Psefu_0170 | Riboflavin biosynthesis protein RibF; SMART: Riboflavin kinase; TIGRFAM: Riboflavin kinase/FAD synthetase; KEGG: pmy:Pmen_0952 bifunctional riboflavin kinase/FMN adenylyltransferase; PFAM: FAD synthetase; Riboflavin kinase; Belongs to the ribF family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.690 |
AEF20716.1 | coaE | Psefu_0738 | Psefu_3794 | Riboflavin biosynthesis protein RibF; SMART: Riboflavin kinase; TIGRFAM: Riboflavin kinase/FAD synthetase; KEGG: pmy:Pmen_0952 bifunctional riboflavin kinase/FMN adenylyltransferase; PFAM: FAD synthetase; Riboflavin kinase; Belongs to the ribF family. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.622 |
AEF20716.1 | guaA | Psefu_0738 | Psefu_1380 | Riboflavin biosynthesis protein RibF; SMART: Riboflavin kinase; TIGRFAM: Riboflavin kinase/FAD synthetase; KEGG: pmy:Pmen_0952 bifunctional riboflavin kinase/FMN adenylyltransferase; PFAM: FAD synthetase; Riboflavin kinase; Belongs to the ribF family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.410 |
AEF21161.1 | AEF24256.1 | Psefu_1184 | Psefu_4304 | PFAM: Acyl carrier protein phosphodiesterase; KEGG: pmy:Pmen_1122 hypothetical protein. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.900 |
AEF21161.1 | coaD | Psefu_1184 | Psefu_0170 | PFAM: Acyl carrier protein phosphodiesterase; KEGG: pmy:Pmen_1122 hypothetical protein. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.903 |
AEF21161.1 | coaX | Psefu_1184 | Psefu_0624 | PFAM: Acyl carrier protein phosphodiesterase; KEGG: pmy:Pmen_1122 hypothetical protein. | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.900 |
AEF21393.1 | coaD | Psefu_1417 | Psefu_0170 | Hypothetical protein; Manually curated; KEGG: gpb:HDN1F_33590 hypothetical protein. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.755 |
AEF24256.1 | AEF20716.1 | Psefu_4304 | Psefu_0738 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Riboflavin biosynthesis protein RibF; SMART: Riboflavin kinase; TIGRFAM: Riboflavin kinase/FAD synthetase; KEGG: pmy:Pmen_0952 bifunctional riboflavin kinase/FMN adenylyltransferase; PFAM: FAD synthetase; Riboflavin kinase; Belongs to the ribF family. | 0.677 |
AEF24256.1 | AEF21161.1 | Psefu_4304 | Psefu_1184 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | PFAM: Acyl carrier protein phosphodiesterase; KEGG: pmy:Pmen_1122 hypothetical protein. | 0.900 |
AEF24256.1 | coaD | Psefu_4304 | Psefu_0170 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.949 |
AEF24256.1 | coaE | Psefu_4304 | Psefu_3794 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.613 |
AEF24256.1 | coaX | Psefu_4304 | Psefu_0624 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.944 |
coaD | AEF20160.1 | Psefu_0170 | Psefu_0174 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. | 0.874 |
coaD | AEF20277.1 | Psefu_0170 | Psefu_0293 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | KEGG: pmy:Pmen_4387 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00255; PFAM: YicC-like, N-terminal; Domain of unknown function DUF1732. | 0.724 |
coaD | AEF20716.1 | Psefu_0170 | Psefu_0738 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Riboflavin biosynthesis protein RibF; SMART: Riboflavin kinase; TIGRFAM: Riboflavin kinase/FAD synthetase; KEGG: pmy:Pmen_0952 bifunctional riboflavin kinase/FMN adenylyltransferase; PFAM: FAD synthetase; Riboflavin kinase; Belongs to the ribF family. | 0.690 |
coaD | AEF21161.1 | Psefu_0170 | Psefu_1184 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | PFAM: Acyl carrier protein phosphodiesterase; KEGG: pmy:Pmen_1122 hypothetical protein. | 0.903 |
coaD | AEF21393.1 | Psefu_0170 | Psefu_1417 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Hypothetical protein; Manually curated; KEGG: gpb:HDN1F_33590 hypothetical protein. | 0.755 |