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trpD trpD trpE trpE AEF20576.1 AEF20576.1 trpC trpC trpF trpF trpA trpA trpB trpB AEF22663.1 AEF22663.1 AEF21989.1 AEF21989.1 aroC aroC aroA aroA
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query proteins and first shell of interactors
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Predicted Interactions
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protein homology
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trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (348 aa)    
Predicted Functional Partners:
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
 
 0.999
AEF20576.1
TIGRFAM: Anthranilate synthase, glutamine amidotransferase domain; KEGG: pmy:Pmen_3946 anthranilate synthase component II; PFAM: Glutamine amidotransferase class-I, C-terminal.
 
 0.999
trpC
KEGG: psb:Psyr_4579 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
  
 0.999
trpF
PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: pmy:Pmen_2716 N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family.
 
 0.998
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.983
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
  
 0.983
AEF22663.1
TIGRFAM: Para-aminobenzoate synthase, component I; KEGG: pmy:Pmen_2540 aminodeoxychorismate synthase, subunit I; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal.
 
 
 0.983
AEF21989.1
Chorismate mutase; TIGRFAM: Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain; PFAM: Prephenate dehydratase; Chorismate mutase, type II; Amino acid-binding ACT; KEGG: pmy:Pmen_1850 prephenate dehydratase; SMART: Chorismate mutase.
 
  
 0.696
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.654
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
   
 0.617
Your Current Organism:
Pseudomonas fulva
NCBI taxonomy Id: 743720
Other names: P. fulva 12-X, Pseudomonas fulva 12-X, Pseudomonas fulva str. 12-X, Pseudomonas fulva strain 12-X
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