node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEF20361.1 | AEF20663.1 | Psefu_0378 | Psefu_0685 | KEGG: pmy:Pmen_0263 HAD family hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.945 |
AEF20361.1 | AEF20665.1 | Psefu_0378 | Psefu_0687 | KEGG: pmy:Pmen_0263 HAD family hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase. | Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; KEGG: pmy:Pmen_3856 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | 0.904 |
AEF20361.1 | AEF20716.1 | Psefu_0378 | Psefu_0738 | KEGG: pmy:Pmen_0263 HAD family hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase. | Riboflavin biosynthesis protein RibF; SMART: Riboflavin kinase; TIGRFAM: Riboflavin kinase/FAD synthetase; KEGG: pmy:Pmen_0952 bifunctional riboflavin kinase/FMN adenylyltransferase; PFAM: FAD synthetase; Riboflavin kinase; Belongs to the ribF family. | 0.918 |
AEF20361.1 | ribH | Psefu_0378 | Psefu_0686 | KEGG: pmy:Pmen_0263 HAD family hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.902 |
AEF20361.1 | ribH-2 | Psefu_0378 | Psefu_0689 | KEGG: pmy:Pmen_0263 HAD family hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.902 |
AEF20663.1 | AEF20361.1 | Psefu_0685 | Psefu_0378 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | KEGG: pmy:Pmen_0263 HAD family hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase. | 0.945 |
AEF20663.1 | AEF20665.1 | Psefu_0685 | Psefu_0687 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; KEGG: pmy:Pmen_3856 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | 0.999 |
AEF20663.1 | AEF20716.1 | Psefu_0685 | Psefu_0738 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin biosynthesis protein RibF; SMART: Riboflavin kinase; TIGRFAM: Riboflavin kinase/FAD synthetase; KEGG: pmy:Pmen_0952 bifunctional riboflavin kinase/FMN adenylyltransferase; PFAM: FAD synthetase; Riboflavin kinase; Belongs to the ribF family. | 0.817 |
AEF20663.1 | nusB | Psefu_0685 | Psefu_0690 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.756 |
AEF20663.1 | ribA | Psefu_0685 | Psefu_3777 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.998 |
AEF20663.1 | ribB | Psefu_0685 | Psefu_0084 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.999 |
AEF20663.1 | ribB-2 | Psefu_0685 | Psefu_0688 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.999 |
AEF20663.1 | ribH | Psefu_0685 | Psefu_0686 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.975 |
AEF20663.1 | ribH-2 | Psefu_0685 | Psefu_0689 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.983 |
AEF20663.1 | thiL | Psefu_0685 | Psefu_0691 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.616 |
AEF20665.1 | AEF20361.1 | Psefu_0687 | Psefu_0378 | Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; KEGG: pmy:Pmen_3856 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | KEGG: pmy:Pmen_0263 HAD family hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase. | 0.904 |
AEF20665.1 | AEF20663.1 | Psefu_0687 | Psefu_0685 | Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; KEGG: pmy:Pmen_3856 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
AEF20665.1 | AEF20716.1 | Psefu_0687 | Psefu_0738 | Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; KEGG: pmy:Pmen_3856 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | Riboflavin biosynthesis protein RibF; SMART: Riboflavin kinase; TIGRFAM: Riboflavin kinase/FAD synthetase; KEGG: pmy:Pmen_0952 bifunctional riboflavin kinase/FMN adenylyltransferase; PFAM: FAD synthetase; Riboflavin kinase; Belongs to the ribF family. | 0.943 |
AEF20665.1 | nusB | Psefu_0687 | Psefu_0690 | Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; KEGG: pmy:Pmen_3856 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.582 |
AEF20665.1 | ribA | Psefu_0687 | Psefu_3777 | Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; KEGG: pmy:Pmen_3856 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.995 |