STRINGSTRING
AEF21475.1 AEF21475.1 AEF21474.1 AEF21474.1 AEF20274.1 AEF20274.1 pyrR pyrR sthA sthA dcd dcd pncB pncB cmk cmk nudC nudC cpdA cpdA AEF20921.1 AEF20921.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEF21475.1MazG family protein; KEGG: pmy:Pmen_1736 nucleoside triphosphate pyrophosphohydrolase; TIGRFAM: NTP pyrophosphohydrolase MazG, bacterial; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core. (275 aa)    
Predicted Functional Partners:
AEF21474.1
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
 
 0.977
AEF20274.1
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
 
 0.936
pyrR
Bifunctional protein pyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
 
  
  0.922
sthA
Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
  
 0.922
dcd
Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.
     
 0.922
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
     
 0.922
cmk
PFAM: Cytidylate kinase domain; TIGRFAM: Cytidylate kinase; HAMAP: Cytidylate kinase; KEGG: pmy:Pmen_1853 cytidylate kinase.
 
  
  0.919
nudC
HAMAP: NADH pyrophosphatase NudC; KEGG: pfl:PFL_3266 NADH pyrophosphatase; PFAM: NUDIX hydrolase domain; NADH pyrophosphatase-like, N-terminal; Zinc ribbon, NADH pyrophosphatase; Belongs to the Nudix hydrolase family. NudC subfamily.
     
 0.919
cpdA
Calcineurin phosphoesterase domain protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
 
  
  0.917
AEF20921.1
PFAM: Phosphoribosyltransferase; KEGG: pmy:Pmen_0947 hypoxanthine-guanine phosphoribosyltransferase.
    
  0.914
Your Current Organism:
Pseudomonas fulva
NCBI taxonomy Id: 743720
Other names: P. fulva 12-X, Pseudomonas fulva 12-X, Pseudomonas fulva str. 12-X, Pseudomonas fulva strain 12-X
Server load: low (16%) [HD]