STRINGSTRING
AEF21518.1 AEF21518.1 AEF22464.1 AEF22464.1 iscS iscS tusA tusA cysC cysC AEF24362.1 AEF24362.1 AEF21517.1 AEF21517.1 thiI thiI AEF20207.1 AEF20207.1 AEF24296.1 AEF24296.1 AEF22465.1 AEF22465.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEF21518.1PFAM: SirA-like; KEGG: nve:NEMVE_v1g151714 hypothetical protein; Belongs to the sulfur carrier protein TusA family. (83 aa)    
Predicted Functional Partners:
AEF22464.1
Sulfur relay protein TusD/DsrE; KEGG: pen:PSEEN2223 sulfur transfer complex subunit TusD; TIGRFAM: Sulphur relay, TusD/DsrE; PFAM: Sulphur relay, DsrE/F-like protein.
 
 
 0.987
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
   
 0.975
tusA
Sulfurtransferase tusA; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family.
  
  
 
0.913
cysC
Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
  
 0.678
AEF24362.1
PFAM: Domain of unknown function DUF395, YeeE/YedE; KEGG: pag:PLES_58251 hypothetical protein.
  
  
 0.623
AEF21517.1
Peptidase M48 Ste24p; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
       0.607
thiI
tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
  
 0.489
AEF20207.1
Pyridine nucleotide-disulfide oxidoreductase family protein; KEGG: pmy:Pmen_4368 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: Pyridine nucleotide-disulphide oxidoreductase family protein, N-terminal; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
     
 0.484
AEF24296.1
KEGG: hse:Hsero_3759 gluconate 2-dehydrogenase; PFAM: Cytochrome c, class I.
     
 0.465
AEF22465.1
KEGG: pmy:Pmen_2378 sulfur relay protein TusC; TIGRFAM: Sulphur relay, TusC/DsrF; PFAM: Sulphur relay, DsrE/F-like protein; Belongs to the DsrF/TusC family.
 
   
 0.441
Your Current Organism:
Pseudomonas fulva
NCBI taxonomy Id: 743720
Other names: P. fulva 12-X, Pseudomonas fulva 12-X, Pseudomonas fulva str. 12-X, Pseudomonas fulva strain 12-X
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.