node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEF20040.1 | AEF21847.1 | Psefu_0053 | Psefu_1874 | precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; KEGG: pmy:Pmen_4574 precorrin-6Y C5,15-methyltransferase (decarboxylating) / precorrin-3 methyltransferase; PFAM: Tetrapyrrole methylase; Cobalamin (vitamin B12) biosynthesis CbiG, core. | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.782 |
AEF20040.1 | AEF21849.1 | Psefu_0053 | Psefu_1876 | precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; KEGG: pmy:Pmen_4574 precorrin-6Y C5,15-methyltransferase (decarboxylating) / precorrin-3 methyltransferase; PFAM: Tetrapyrrole methylase; Cobalamin (vitamin B12) biosynthesis CbiG, core. | KEGG: pst:PSPTO_1710 nitroreductase family protein; TIGRFAM: Cob(II)yrinic acid a,c-diamide reductase; PFAM: Nitroreductase-like. | 0.611 |
AEF20040.1 | AEF21851.1 | Psefu_0053 | Psefu_1878 | precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; KEGG: pmy:Pmen_4574 precorrin-6Y C5,15-methyltransferase (decarboxylating) / precorrin-3 methyltransferase; PFAM: Tetrapyrrole methylase; Cobalamin (vitamin B12) biosynthesis CbiG, core. | KEGG: psa:PST_1296 threonine-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase, class I/classII. | 0.647 |
AEF20040.1 | AEF21853.1 | Psefu_0053 | Psefu_1880 | precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; KEGG: pmy:Pmen_4574 precorrin-6Y C5,15-methyltransferase (decarboxylating) / precorrin-3 methyltransferase; PFAM: Tetrapyrrole methylase; Cobalamin (vitamin B12) biosynthesis CbiG, core. | Adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.832 |
AEF20040.1 | AEF21855.1 | Psefu_0053 | Psefu_1882 | precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; KEGG: pmy:Pmen_4574 precorrin-6Y C5,15-methyltransferase (decarboxylating) / precorrin-3 methyltransferase; PFAM: Tetrapyrrole methylase; Cobalamin (vitamin B12) biosynthesis CbiG, core. | TIGRFAM: Alpha-ribazole phosphatase, CobC; PFAM: Histidine phosphatase superfamily, clade-1; KEGG: pmy:Pmen_1758 phosphoglycerate mutase; SMART: Histidine phosphatase superfamily, clade-1. | 0.591 |
AEF20040.1 | cobB | Psefu_0053 | Psefu_1875 | precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; KEGG: pmy:Pmen_4574 precorrin-6Y C5,15-methyltransferase (decarboxylating) / precorrin-3 methyltransferase; PFAM: Tetrapyrrole methylase; Cobalamin (vitamin B12) biosynthesis CbiG, core. | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.977 |
AEF20040.1 | cobD | Psefu_0053 | Psefu_1877 | precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; KEGG: pmy:Pmen_4574 precorrin-6Y C5,15-methyltransferase (decarboxylating) / precorrin-3 methyltransferase; PFAM: Tetrapyrrole methylase; Cobalamin (vitamin B12) biosynthesis CbiG, core. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.876 |
AEF20040.1 | cobQ | Psefu_0053 | Psefu_1879 | precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; KEGG: pmy:Pmen_4574 precorrin-6Y C5,15-methyltransferase (decarboxylating) / precorrin-3 methyltransferase; PFAM: Tetrapyrrole methylase; Cobalamin (vitamin B12) biosynthesis CbiG, core. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.993 |
AEF20040.1 | cobS | Psefu_0053 | Psefu_1883 | precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; KEGG: pmy:Pmen_4574 precorrin-6Y C5,15-methyltransferase (decarboxylating) / precorrin-3 methyltransferase; PFAM: Tetrapyrrole methylase; Cobalamin (vitamin B12) biosynthesis CbiG, core. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.969 |
AEF20040.1 | cobT | Psefu_0053 | Psefu_1881 | precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; KEGG: pmy:Pmen_4574 precorrin-6Y C5,15-methyltransferase (decarboxylating) / precorrin-3 methyltransferase; PFAM: Tetrapyrrole methylase; Cobalamin (vitamin B12) biosynthesis CbiG, core. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.864 |
AEF21847.1 | AEF20040.1 | Psefu_1874 | Psefu_0053 | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; KEGG: pmy:Pmen_4574 precorrin-6Y C5,15-methyltransferase (decarboxylating) / precorrin-3 methyltransferase; PFAM: Tetrapyrrole methylase; Cobalamin (vitamin B12) biosynthesis CbiG, core. | 0.782 |
AEF21847.1 | AEF21849.1 | Psefu_1874 | Psefu_1876 | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | KEGG: pst:PSPTO_1710 nitroreductase family protein; TIGRFAM: Cob(II)yrinic acid a,c-diamide reductase; PFAM: Nitroreductase-like. | 0.922 |
AEF21847.1 | AEF21851.1 | Psefu_1874 | Psefu_1878 | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | KEGG: psa:PST_1296 threonine-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase, class I/classII. | 0.993 |
AEF21847.1 | AEF21853.1 | Psefu_1874 | Psefu_1880 | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.997 |
AEF21847.1 | AEF21855.1 | Psefu_1874 | Psefu_1882 | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | TIGRFAM: Alpha-ribazole phosphatase, CobC; PFAM: Histidine phosphatase superfamily, clade-1; KEGG: pmy:Pmen_1758 phosphoglycerate mutase; SMART: Histidine phosphatase superfamily, clade-1. | 0.864 |
AEF21847.1 | cobB | Psefu_1874 | Psefu_1875 | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.993 |
AEF21847.1 | cobD | Psefu_1874 | Psefu_1877 | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.995 |
AEF21847.1 | cobQ | Psefu_1874 | Psefu_1879 | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.996 |
AEF21847.1 | cobS | Psefu_1874 | Psefu_1883 | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.994 |
AEF21847.1 | cobT | Psefu_1874 | Psefu_1881 | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.924 |