STRINGSTRING
hflD hflD mnmA mnmA rnt rnt AEF21866.1 AEF21866.1 AEF22288.1 AEF22288.1 nudJ nudJ AEF22698.1 AEF22698.1 AEF22287.1 AEF22287.1 truD truD hisG hisG AEF20363.1 AEF20363.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hflDHigh frequency lysogenization protein hflD; KEGG: ppw:PputW619_3419 hypothetical protein; HAMAP: Uncharacterised protein family UPF0274; PFAM: Uncharacterised protein family UPF0274. (206 aa)    
Predicted Functional Partners:
mnmA
tRNA-specific 2-thiouridylase mnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
  
  
 0.961
rnt
Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.
  
    0.722
AEF21866.1
UPF0745 protein ycgL; KEGG: pen:PSEEN4034 hypothetical protein; HAMAP: Uncharacterised protein family UPF0745; PFAM: Uncharacterised protein family UPF0745.
  
    0.718
AEF22288.1
TIGRFAM: Adenylosuccinate lyase; KEGG: pmy:Pmen_2402 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase C-terminal/plant; Lyase 1, N-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
    0.671
nudJ
PFAM: NUDIX hydrolase domain; KEGG: pau:PA14_30160 hypothetical protein; Belongs to the Nudix hydrolase family. NudJ subfamily.
       0.617
AEF22698.1
PFAM: Protein of unknown function DUF177; KEGG: pfl:PFL_1792 hypothetical protein.
  
    0.614
AEF22287.1
Cupin, JmjC-type; KEGG: pmy:Pmen_2403 cupin 4 family protein; PFAM: Cupin, JmjC-type; SMART: Transcription factor jumonji/aspartyl beta-hydroxylase.
 
  
 0.588
truD
tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
  
    0.547
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
   
    0.545
AEF20363.1
PFAM: Protein of unknown function DUF484; KEGG: pmy:Pmen_0265 hypothetical protein.
  
     0.513
Your Current Organism:
Pseudomonas fulva
NCBI taxonomy Id: 743720
Other names: P. fulva 12-X, Pseudomonas fulva 12-X, Pseudomonas fulva str. 12-X, Pseudomonas fulva strain 12-X
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.