STRINGSTRING
AEF23152.1 AEF23152.1 AEF23151.1 AEF23151.1 dnaE2 dnaE2 AEF19989.1 AEF19989.1 AEF24088.1 AEF24088.1 lexA lexA recA recA polA polA AEF22876.1 AEF22876.1 AEF22056.1 AEF22056.1 AEF21412.1 AEF21412.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
AEF23152.1KEGG: pmy:Pmen_1935 DNA repair nucleotidyltransferase/DNA polymerase-like protein. (469 aa)    
Predicted Functional Partners:
AEF23151.1
KEGG: psa:PST_2344 cell division inhibitor SulA, putative.
 
  
 0.997
dnaE2
Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
 
  
 0.989
AEF19989.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.873
AEF24088.1
KEGG: pst:PSPTO_2621 DNA polymerase II; PFAM: DNA-directed DNA polymerase, family B, conserved region; DNA-directed DNA polymerase, family B, exonuclease domain; SMART: DNA-directed DNA polymerase, family B.
  
 0.854
lexA
SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
 
 
 0.842
recA
Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.795
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.667
AEF22876.1
SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
 
  
 0.644
AEF22056.1
Methylated-DNA--(protein)-cysteine S-methyltransferase; PFAM: AlkA, N-terminal; HhH-GPD domain; KEGG: pae:PA1686 DNA-3-methyladenine glycosidase II; SMART: HhH-GPD domain.
  
 
 0.640
AEF21412.1
Phage repressor like transcriptional regulator, XRE family; KEGG: hel:HELO_2105 putative phage repressor; PFAM: Peptidase S24/S26A/S26B, conserved region; Helix-turn-helix type 3; SMART: Helix-turn-helix type 3.
  
 
 0.612
Your Current Organism:
Pseudomonas fulva
NCBI taxonomy Id: 743720
Other names: P. fulva 12-X, Pseudomonas fulva 12-X, Pseudomonas fulva str. 12-X, Pseudomonas fulva strain 12-X
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