node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEF23387.1 | AEF23389.1 | Psefu_3425 | Psefu_3427 | TIGRFAM: Peptidase M50, putative membrane-associated zinc metallopeptidase; PFAM: Peptidase M50; PDZ/DHR/GLGF; KEGG: pmy:Pmen_3046 putative membrane-associated zinc metalloprotease; SMART: PDZ/DHR/GLGF. | PFAM: Phosphatidate cytidylyltransferase; KEGG: pmy:Pmen_3048 phosphatidate cytidylyltransferase; Belongs to the CDS family. | 0.954 |
AEF23387.1 | dxr | Psefu_3425 | Psefu_3426 | TIGRFAM: Peptidase M50, putative membrane-associated zinc metallopeptidase; PFAM: Peptidase M50; PDZ/DHR/GLGF; KEGG: pmy:Pmen_3046 putative membrane-associated zinc metalloprotease; SMART: PDZ/DHR/GLGF. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.903 |
AEF23387.1 | frr | Psefu_3425 | Psefu_3429 | TIGRFAM: Peptidase M50, putative membrane-associated zinc metallopeptidase; PFAM: Peptidase M50; PDZ/DHR/GLGF; KEGG: pmy:Pmen_3046 putative membrane-associated zinc metalloprotease; SMART: PDZ/DHR/GLGF. | Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.842 |
AEF23387.1 | uppS | Psefu_3425 | Psefu_3428 | TIGRFAM: Peptidase M50, putative membrane-associated zinc metallopeptidase; PFAM: Peptidase M50; PDZ/DHR/GLGF; KEGG: pmy:Pmen_3046 putative membrane-associated zinc metalloprotease; SMART: PDZ/DHR/GLGF. | Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.965 |
AEF23389.1 | AEF23387.1 | Psefu_3427 | Psefu_3425 | PFAM: Phosphatidate cytidylyltransferase; KEGG: pmy:Pmen_3048 phosphatidate cytidylyltransferase; Belongs to the CDS family. | TIGRFAM: Peptidase M50, putative membrane-associated zinc metallopeptidase; PFAM: Peptidase M50; PDZ/DHR/GLGF; KEGG: pmy:Pmen_3046 putative membrane-associated zinc metalloprotease; SMART: PDZ/DHR/GLGF. | 0.954 |
AEF23389.1 | dxr | Psefu_3427 | Psefu_3426 | PFAM: Phosphatidate cytidylyltransferase; KEGG: pmy:Pmen_3048 phosphatidate cytidylyltransferase; Belongs to the CDS family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.966 |
AEF23389.1 | frr | Psefu_3427 | Psefu_3429 | PFAM: Phosphatidate cytidylyltransferase; KEGG: pmy:Pmen_3048 phosphatidate cytidylyltransferase; Belongs to the CDS family. | Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.886 |
AEF23389.1 | ispD | Psefu_3427 | Psefu_3410 | PFAM: Phosphatidate cytidylyltransferase; KEGG: pmy:Pmen_3048 phosphatidate cytidylyltransferase; Belongs to the CDS family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.422 |
AEF23389.1 | uppS | Psefu_3427 | Psefu_3428 | PFAM: Phosphatidate cytidylyltransferase; KEGG: pmy:Pmen_3048 phosphatidate cytidylyltransferase; Belongs to the CDS family. | Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.976 |
dxr | AEF23387.1 | Psefu_3426 | Psefu_3425 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | TIGRFAM: Peptidase M50, putative membrane-associated zinc metallopeptidase; PFAM: Peptidase M50; PDZ/DHR/GLGF; KEGG: pmy:Pmen_3046 putative membrane-associated zinc metalloprotease; SMART: PDZ/DHR/GLGF. | 0.903 |
dxr | AEF23389.1 | Psefu_3426 | Psefu_3427 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | PFAM: Phosphatidate cytidylyltransferase; KEGG: pmy:Pmen_3048 phosphatidate cytidylyltransferase; Belongs to the CDS family. | 0.966 |
dxr | dxs | Psefu_3426 | Psefu_3773 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.991 |
dxr | frr | Psefu_3426 | Psefu_3429 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.867 |
dxr | ispD | Psefu_3426 | Psefu_3410 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.992 |
dxr | ispE | Psefu_3426 | Psefu_0922 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.867 |
dxr | ispF | Psefu_3426 | Psefu_3404 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.919 |
dxr | ispG | Psefu_3426 | Psefu_3292 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.879 |
dxr | ispH | Psefu_3426 | Psefu_0744 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.876 |
dxr | uppS | Psefu_3426 | Psefu_3428 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.970 |
dxs | dxr | Psefu_3773 | Psefu_3426 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.991 |