node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEF21475.1 | AEF21596.1 | Psefu_1499 | Psefu_1622 | MazG family protein; KEGG: pmy:Pmen_1736 nucleoside triphosphate pyrophosphohydrolase; TIGRFAM: NTP pyrophosphohydrolase MazG, bacterial; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core. | Cytidyltransferase-related domain protein; TIGRFAM: Cytidyltransferase-related; KEGG: pmy:Pmen_1542 NAD metabolism ATPase/kinase-like protein. | 0.900 |
AEF21475.1 | AEF21844.1 | Psefu_1499 | Psefu_1871 | MazG family protein; KEGG: pmy:Pmen_1736 nucleoside triphosphate pyrophosphohydrolase; TIGRFAM: NTP pyrophosphohydrolase MazG, bacterial; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core. | NAD-dependent deacetylase; KEGG: pst:PSPTO_1704 transcriptional regulator, Sir2 family; HAMAP: NAD-dependent histone deacetylase, silent information regulator Sir2; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2. | 0.901 |
AEF21475.1 | AEF23437.1 | Psefu_1499 | Psefu_3475 | MazG family protein; KEGG: pmy:Pmen_1736 nucleoside triphosphate pyrophosphohydrolase; TIGRFAM: NTP pyrophosphohydrolase MazG, bacterial; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core. | KEGG: pmy:Pmen_4431 NAD(P)(+) transhydrogenase (AB-specific); PFAM: Alanine dehydrogenase/PNT, C-terminal; Alanine dehydrogenase/PNT, N-terminal. | 0.901 |
AEF21475.1 | AEF23438.1 | Psefu_1499 | Psefu_3476 | MazG family protein; KEGG: pmy:Pmen_1736 nucleoside triphosphate pyrophosphohydrolase; TIGRFAM: NTP pyrophosphohydrolase MazG, bacterial; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core. | KEGG: pmy:Pmen_4432 NAD/NADP transhydrogenase alpha subunit-like protein. | 0.901 |
AEF21475.1 | AEF23439.1 | Psefu_1499 | Psefu_3477 | MazG family protein; KEGG: pmy:Pmen_1736 nucleoside triphosphate pyrophosphohydrolase; TIGRFAM: NTP pyrophosphohydrolase MazG, bacterial; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core. | NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.902 |
AEF21475.1 | nadD | Psefu_1499 | Psefu_3629 | MazG family protein; KEGG: pmy:Pmen_1736 nucleoside triphosphate pyrophosphohydrolase; TIGRFAM: NTP pyrophosphohydrolase MazG, bacterial; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.903 |
AEF21475.1 | nadE | Psefu_1499 | Psefu_3995 | MazG family protein; KEGG: pmy:Pmen_1736 nucleoside triphosphate pyrophosphohydrolase; TIGRFAM: NTP pyrophosphohydrolase MazG, bacterial; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.900 |
AEF21475.1 | nadK | Psefu_1499 | Psefu_1823 | MazG family protein; KEGG: pmy:Pmen_1736 nucleoside triphosphate pyrophosphohydrolase; TIGRFAM: NTP pyrophosphohydrolase MazG, bacterial; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.902 |
AEF21475.1 | nudC | Psefu_1499 | Psefu_2265 | MazG family protein; KEGG: pmy:Pmen_1736 nucleoside triphosphate pyrophosphohydrolase; TIGRFAM: NTP pyrophosphohydrolase MazG, bacterial; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core. | HAMAP: NADH pyrophosphatase NudC; KEGG: pfl:PFL_3266 NADH pyrophosphatase; PFAM: NUDIX hydrolase domain; NADH pyrophosphatase-like, N-terminal; Zinc ribbon, NADH pyrophosphatase; Belongs to the Nudix hydrolase family. NudC subfamily. | 0.919 |
AEF21475.1 | sthA | Psefu_1499 | Psefu_2898 | MazG family protein; KEGG: pmy:Pmen_1736 nucleoside triphosphate pyrophosphohydrolase; TIGRFAM: NTP pyrophosphohydrolase MazG, bacterial; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core. | Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.922 |
AEF21596.1 | AEF21475.1 | Psefu_1622 | Psefu_1499 | Cytidyltransferase-related domain protein; TIGRFAM: Cytidyltransferase-related; KEGG: pmy:Pmen_1542 NAD metabolism ATPase/kinase-like protein. | MazG family protein; KEGG: pmy:Pmen_1736 nucleoside triphosphate pyrophosphohydrolase; TIGRFAM: NTP pyrophosphohydrolase MazG, bacterial; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core. | 0.900 |
AEF21596.1 | AEF21844.1 | Psefu_1622 | Psefu_1871 | Cytidyltransferase-related domain protein; TIGRFAM: Cytidyltransferase-related; KEGG: pmy:Pmen_1542 NAD metabolism ATPase/kinase-like protein. | NAD-dependent deacetylase; KEGG: pst:PSPTO_1704 transcriptional regulator, Sir2 family; HAMAP: NAD-dependent histone deacetylase, silent information regulator Sir2; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2. | 0.955 |
AEF21596.1 | AEF23437.1 | Psefu_1622 | Psefu_3475 | Cytidyltransferase-related domain protein; TIGRFAM: Cytidyltransferase-related; KEGG: pmy:Pmen_1542 NAD metabolism ATPase/kinase-like protein. | KEGG: pmy:Pmen_4431 NAD(P)(+) transhydrogenase (AB-specific); PFAM: Alanine dehydrogenase/PNT, C-terminal; Alanine dehydrogenase/PNT, N-terminal. | 0.900 |
AEF21596.1 | AEF23438.1 | Psefu_1622 | Psefu_3476 | Cytidyltransferase-related domain protein; TIGRFAM: Cytidyltransferase-related; KEGG: pmy:Pmen_1542 NAD metabolism ATPase/kinase-like protein. | KEGG: pmy:Pmen_4432 NAD/NADP transhydrogenase alpha subunit-like protein. | 0.900 |
AEF21596.1 | AEF23439.1 | Psefu_1622 | Psefu_3477 | Cytidyltransferase-related domain protein; TIGRFAM: Cytidyltransferase-related; KEGG: pmy:Pmen_1542 NAD metabolism ATPase/kinase-like protein. | NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.900 |
AEF21596.1 | nadD | Psefu_1622 | Psefu_3629 | Cytidyltransferase-related domain protein; TIGRFAM: Cytidyltransferase-related; KEGG: pmy:Pmen_1542 NAD metabolism ATPase/kinase-like protein. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.915 |
AEF21596.1 | nadE | Psefu_1622 | Psefu_3995 | Cytidyltransferase-related domain protein; TIGRFAM: Cytidyltransferase-related; KEGG: pmy:Pmen_1542 NAD metabolism ATPase/kinase-like protein. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.919 |
AEF21596.1 | nadK | Psefu_1622 | Psefu_1823 | Cytidyltransferase-related domain protein; TIGRFAM: Cytidyltransferase-related; KEGG: pmy:Pmen_1542 NAD metabolism ATPase/kinase-like protein. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.907 |
AEF21596.1 | nudC | Psefu_1622 | Psefu_2265 | Cytidyltransferase-related domain protein; TIGRFAM: Cytidyltransferase-related; KEGG: pmy:Pmen_1542 NAD metabolism ATPase/kinase-like protein. | HAMAP: NADH pyrophosphatase NudC; KEGG: pfl:PFL_3266 NADH pyrophosphatase; PFAM: NUDIX hydrolase domain; NADH pyrophosphatase-like, N-terminal; Zinc ribbon, NADH pyrophosphatase; Belongs to the Nudix hydrolase family. NudC subfamily. | 0.900 |
AEF21596.1 | sthA | Psefu_1622 | Psefu_2898 | Cytidyltransferase-related domain protein; TIGRFAM: Cytidyltransferase-related; KEGG: pmy:Pmen_1542 NAD metabolism ATPase/kinase-like protein. | Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.900 |