STRINGSTRING
AEF23809.1 AEF23809.1 AEF21141.1 AEF21141.1 gcvP gcvP AEF23810.1 AEF23810.1 gcvT gcvT thyA thyA gcvH gcvH gcvH-2 gcvH-2 folD folD AEF20998.1 AEF20998.1 AEF20321.1 AEF20321.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
AEF23809.1PFAM: Amino acid-binding ACT; KEGG: pmy:Pmen_4094 amino acid-binding ACT domain-containing protein. (172 aa)    
Predicted Functional Partners:
AEF21141.1
KEGG: pfl:PFL_1146 hypothetical protein.
  
    0.812
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
 
 0.779
AEF23810.1
PFAM: GCN5-related N-acetyltransferase (GNAT) domain; KEGG: pau:PA14_06300 GNAT family acetyltransferase.
  
    0.709
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
 
  
 0.582
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.550
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
    
  0.542
gcvH-2
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
    
  0.542
folD
Bifunctional protein folD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
 
  0.542
AEF20998.1
TIGRFAM: Glycine cleavage system T protein; KEGG: pmy:Pmen_1343 glycine cleavage system T protein; PFAM: Glycine cleavage T-protein, N-terminal; Glycine cleavage T-protein, C-terminal barrel.
    
 0.528
AEF20321.1
TIGRFAM: 5,10-methylenetetrahydrofolate reductase; KEGG: psa:PST_3936 5,10-methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
     
  0.499
Your Current Organism:
Pseudomonas fulva
NCBI taxonomy Id: 743720
Other names: P. fulva 12-X, Pseudomonas fulva 12-X, Pseudomonas fulva str. 12-X, Pseudomonas fulva strain 12-X
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