node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEF22511.1 | cysC | Psefu_2546 | Psefu_3655 | KEGG: pmy:Pmen_2545 phosphoadenylylsulfate reductase (thioredoxin); PFAM: Phosphoadenosine phosphosulphate reductase. | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.999 |
AEF22511.1 | cysD | Psefu_2546 | Psefu_3656 | KEGG: pmy:Pmen_2545 phosphoadenylylsulfate reductase (thioredoxin); PFAM: Phosphoadenosine phosphosulphate reductase. | Sulfate adenylyltransferase subunit 2; PFAM: Phosphoadenosine phosphosulphate reductase; TIGRFAM: Sulphate adenylyltransferase, small subunit; HAMAP: Sulphate adenylyltransferase, small subunit; KEGG: psp:PSPPH_4133 sulfate adenylyltransferase subunit 2. | 0.903 |
AEF22511.1 | cysG | Psefu_2546 | Psefu_2338 | KEGG: pmy:Pmen_2545 phosphoadenylylsulfate reductase (thioredoxin); PFAM: Phosphoadenosine phosphosulphate reductase. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.920 |
AEF22511.1 | cysQ | Psefu_2546 | Psefu_4069 | KEGG: pmy:Pmen_2545 phosphoadenylylsulfate reductase (thioredoxin); PFAM: Phosphoadenosine phosphosulphate reductase. | 3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.940 |
AEF22923.1 | AEF23269.1 | Psefu_2959 | Psefu_3307 | PFAM: Inositol monophosphatase; KEGG: psa:PST_1593 inositol-1-monophosphatase. | PFAM: Inositol monophosphatase; KEGG: pmy:Pmen_3515 inositol-phosphate phosphatase. | 0.924 |
AEF22923.1 | cysQ | Psefu_2959 | Psefu_4069 | PFAM: Inositol monophosphatase; KEGG: psa:PST_1593 inositol-1-monophosphatase. | 3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.672 |
AEF23269.1 | AEF22923.1 | Psefu_3307 | Psefu_2959 | PFAM: Inositol monophosphatase; KEGG: pmy:Pmen_3515 inositol-phosphate phosphatase. | PFAM: Inositol monophosphatase; KEGG: psa:PST_1593 inositol-1-monophosphatase. | 0.924 |
AEF23269.1 | cysQ | Psefu_3307 | Psefu_4069 | PFAM: Inositol monophosphatase; KEGG: pmy:Pmen_3515 inositol-phosphate phosphatase. | 3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.448 |
AEF24025.1 | AEF24026.1 | Psefu_4070 | Psefu_4071 | PFAM: NUDIX hydrolase domain; KEGG: psa:PST_0318 ADP-ribose diphosphatase NudE. | KEGG: pfo:Pfl01_0283 HAD family hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase. | 0.646 |
AEF24025.1 | cysQ | Psefu_4070 | Psefu_4069 | PFAM: NUDIX hydrolase domain; KEGG: psa:PST_0318 ADP-ribose diphosphatase NudE. | 3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.836 |
AEF24026.1 | AEF24025.1 | Psefu_4071 | Psefu_4070 | KEGG: pfo:Pfl01_0283 HAD family hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase. | PFAM: NUDIX hydrolase domain; KEGG: psa:PST_0318 ADP-ribose diphosphatase NudE. | 0.646 |
AEF24026.1 | cysQ | Psefu_4071 | Psefu_4069 | KEGG: pfo:Pfl01_0283 HAD family hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase. | 3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.607 |
AEF24026.1 | thyA | Psefu_4071 | Psefu_4273 | KEGG: pfo:Pfl01_0283 HAD family hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.907 |
cysC | AEF22511.1 | Psefu_3655 | Psefu_2546 | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | KEGG: pmy:Pmen_2545 phosphoadenylylsulfate reductase (thioredoxin); PFAM: Phosphoadenosine phosphosulphate reductase. | 0.999 |
cysC | cysD | Psefu_3655 | Psefu_3656 | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | Sulfate adenylyltransferase subunit 2; PFAM: Phosphoadenosine phosphosulphate reductase; TIGRFAM: Sulphate adenylyltransferase, small subunit; HAMAP: Sulphate adenylyltransferase, small subunit; KEGG: psp:PSPPH_4133 sulfate adenylyltransferase subunit 2. | 0.999 |
cysC | cysG | Psefu_3655 | Psefu_2338 | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.983 |
cysC | cysQ | Psefu_3655 | Psefu_4069 | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.977 |
cysD | AEF22511.1 | Psefu_3656 | Psefu_2546 | Sulfate adenylyltransferase subunit 2; PFAM: Phosphoadenosine phosphosulphate reductase; TIGRFAM: Sulphate adenylyltransferase, small subunit; HAMAP: Sulphate adenylyltransferase, small subunit; KEGG: psp:PSPPH_4133 sulfate adenylyltransferase subunit 2. | KEGG: pmy:Pmen_2545 phosphoadenylylsulfate reductase (thioredoxin); PFAM: Phosphoadenosine phosphosulphate reductase. | 0.903 |
cysD | cysC | Psefu_3656 | Psefu_3655 | Sulfate adenylyltransferase subunit 2; PFAM: Phosphoadenosine phosphosulphate reductase; TIGRFAM: Sulphate adenylyltransferase, small subunit; HAMAP: Sulphate adenylyltransferase, small subunit; KEGG: psp:PSPPH_4133 sulfate adenylyltransferase subunit 2. | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.999 |
cysD | cysG | Psefu_3656 | Psefu_2338 | Sulfate adenylyltransferase subunit 2; PFAM: Phosphoadenosine phosphosulphate reductase; TIGRFAM: Sulphate adenylyltransferase, small subunit; HAMAP: Sulphate adenylyltransferase, small subunit; KEGG: psp:PSPPH_4133 sulfate adenylyltransferase subunit 2. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.918 |