STRINGSTRING
thiG thiG AGA84877.1 AGA84877.1 AGA87858.1 AGA87858.1 thiI thiI thiE thiE thiC thiC AGA85144.1 AGA85144.1 AGA85679.1 AGA85679.1 dxs dxs AGA85696.1 AGA85696.1 AGA87664.1 AGA87664.1
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second shell of interactors
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textmining
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protein homology
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thiGPutative enzyme of thiazole biosynthesis; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (264 aa)    
Predicted Functional Partners:
AGA84877.1
Sulfur carrier protein ThiS; PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS.
 
 
 0.997
AGA87858.1
Glycine oxidase; PFAM: FAD dependent oxidoreductase; TIGRFAM: glycine oxidase ThiO.
 
 0.996
thiI
(ThiS-adenylate) sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
 
 0.976
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.975
thiC
Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
  
 0.972
AGA85144.1
PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; manually curated.
 
  
 0.954
AGA85679.1
Dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis; PFAM: MoeZ/MoeB domain; ThiF family.
 
  
 0.943
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
     
 0.927
AGA85696.1
8-oxo-dGTPase; PFAM: NUDIX domain; Thiamine monophosphate synthase/TENI; TIGRFAM: mutator mutT protein; thiamine-phosphate pyrophosphorylase.
 
  
 0.924
AGA87664.1
PFAM: ThiS family; TIGRFAM: molybdopterin converting factor, subunit 1, non-archaeal.
   
 
 0.807
Your Current Organism:
Pseudomonas stutzeri
NCBI taxonomy Id: 644801
Other names: P. stutzeri RCH2, Pseudomonas stutzeri RCH2, Pseudomonas stutzeri str. RCH2, Pseudomonas stutzeri strain RCH2
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