STRINGSTRING
AGA84890.1 AGA84890.1 metXS metXS AGA84889.1 AGA84889.1 AGA86889.1 AGA86889.1 AGA84888.1 AGA84888.1 thrB thrB AGA84886.1 AGA84886.1 AGA84887.1 AGA84887.1 AGA84892.1 AGA84892.1 AGA88162.1 AGA88162.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGA84890.1PFAM: Methionine biosynthesis protein MetW; TIGRFAM: methionine biosynthesis protein MetW. (199 aa)    
Predicted Functional Partners:
metXS
Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
  
 0.997
AGA84889.1
Hypothetical protein.
      0.920
AGA86889.1
PFAM: alpha/beta hydrolase fold; TIGRFAM: homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family.
 
  
 0.856
AGA84888.1
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
       0.726
thrB
Homoserine kinase; PFAM: Phosphotransferase enzyme family; TIGRFAM: homoserine kinase, Neisseria type; Belongs to the pseudomonas-type ThrB family.
  
     0.623
AGA84886.1
PFAM: Protein of unknown function (DUF3392).
       0.577
AGA84887.1
Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
       0.577
AGA84892.1
PFAM: Dynamin family.
       0.549
AGA88162.1
O-acetylhomoserine sulfhydrolase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase.
 
   
 0.406
Your Current Organism:
Pseudomonas stutzeri
NCBI taxonomy Id: 644801
Other names: P. stutzeri RCH2, Pseudomonas stutzeri RCH2, Pseudomonas stutzeri str. RCH2, Pseudomonas stutzeri strain RCH2
Server load: low (18%) [HD]