node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGA86321.1 | AGA87622.1 | Psest_1772 | Psest_3126 | PFAM: Aminotransferase class I and II. | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. | 0.545 |
AGA86321.1 | AGA88005.1 | Psest_1772 | Psest_3516 | PFAM: Aminotransferase class I and II. | PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.910 |
AGA86321.1 | ilvD | Psest_1772 | Psest_0234 | PFAM: Aminotransferase class I and II. | PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.916 |
AGA86321.1 | ilvE | Psest_1772 | Psest_0450 | PFAM: Aminotransferase class I and II. | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.916 |
AGA86321.1 | leuA | Psest_1772 | Psest_1056 | PFAM: Aminotransferase class I and II. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.906 |
AGA86321.1 | leuA-2 | Psest_1772 | Psest_1277 | PFAM: Aminotransferase class I and II. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.906 |
AGA86853.1 | AGA87622.1 | Psest_2327 | Psest_3126 | PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein. | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. | 0.931 |
AGA86853.1 | ilvA | Psest_2327 | Psest_3866 | PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.915 |
AGA86853.1 | ilvE | Psest_2327 | Psest_0450 | PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein. | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.852 |
AGA87622.1 | AGA86321.1 | Psest_3126 | Psest_1772 | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. | PFAM: Aminotransferase class I and II. | 0.545 |
AGA87622.1 | AGA86853.1 | Psest_3126 | Psest_2327 | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. | PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein. | 0.931 |
AGA87622.1 | AGA88005.1 | Psest_3126 | Psest_3516 | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. | PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.817 |
AGA87622.1 | ilvA | Psest_3126 | Psest_3866 | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.926 |
AGA87622.1 | ilvD | Psest_3126 | Psest_0234 | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. | PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.894 |
AGA87622.1 | ilvE | Psest_3126 | Psest_0450 | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.976 |
AGA87622.1 | leuA | Psest_3126 | Psest_1056 | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.879 |
AGA87622.1 | leuA-2 | Psest_3126 | Psest_1277 | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.879 |
AGA88005.1 | AGA86321.1 | Psest_3516 | Psest_1772 | PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | PFAM: Aminotransferase class I and II. | 0.910 |
AGA88005.1 | AGA87622.1 | Psest_3516 | Psest_3126 | PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. | 0.817 |
AGA88005.1 | ilvD | Psest_3516 | Psest_0234 | PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.913 |