node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGA85141.1 | AGA85144.1 | Psest_0534 | Psest_0537 | Hypothetical protein. | PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; manually curated. | 0.630 |
AGA85141.1 | hemL | Psest_0534 | Psest_0535 | Hypothetical protein. | PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase. | 0.797 |
AGA85141.1 | thiE | Psest_0534 | Psest_0536 | Hypothetical protein. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.647 |
AGA85144.1 | AGA85141.1 | Psest_0537 | Psest_0534 | PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; manually curated. | Hypothetical protein. | 0.630 |
AGA85144.1 | cysG | Psest_0537 | Psest_2037 | PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; manually curated. | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.417 |
AGA85144.1 | hemL | Psest_0537 | Psest_0535 | PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; manually curated. | PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase. | 0.711 |
AGA85144.1 | thiE | Psest_0537 | Psest_0536 | PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; manually curated. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.999 |
AGA85403.1 | AGA86470.1 | Psest_0810 | Psest_1925 | uroporphyrinogen-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | uroporphyrinogen-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.912 |
AGA85403.1 | AGA88210.1 | Psest_0810 | Psest_3733 | uroporphyrinogen-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.870 |
AGA85403.1 | cysG | Psest_0810 | Psest_2037 | uroporphyrinogen-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.963 |
AGA85403.1 | hemA | Psest_0810 | Psest_1112 | uroporphyrinogen-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.767 |
AGA85403.1 | hemC | Psest_0810 | Psest_3748 | uroporphyrinogen-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.978 |
AGA85403.1 | hemL | Psest_0810 | Psest_0535 | uroporphyrinogen-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase. | 0.737 |
AGA86470.1 | AGA85403.1 | Psest_1925 | Psest_0810 | uroporphyrinogen-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | uroporphyrinogen-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.912 |
AGA86470.1 | AGA88210.1 | Psest_1925 | Psest_3733 | uroporphyrinogen-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.869 |
AGA86470.1 | cysG | Psest_1925 | Psest_2037 | uroporphyrinogen-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.965 |
AGA86470.1 | hemA | Psest_1925 | Psest_1112 | uroporphyrinogen-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.761 |
AGA86470.1 | hemC | Psest_1925 | Psest_3748 | uroporphyrinogen-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.980 |
AGA86470.1 | hemL | Psest_1925 | Psest_0535 | uroporphyrinogen-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase. | 0.739 |
AGA88210.1 | AGA85403.1 | Psest_3733 | Psest_0810 | PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | uroporphyrinogen-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.870 |